Liver abscess in advanced hepatocellular carcinoma after sorafenib treatment.

Seung Kak Shin, Young Kul Jung, Hyun Hwa Yoon, Oh Sang Kwon, Yun Soo Kim, Duck Joo Choi, Ju Hyun Kim

    Research output: Contribution to journalArticlepeer-review

    4 Citations (Scopus)


    Hepatocellular carcinoma (HCC) is a critical global health issue and the third most common cause of cancer-related deaths worldwide. The majority of patients who present HCC are already at an advanced stage and their tumors are unresectable. Sorafenib is a multi-kinase inhibitor of the vascular endothelial growth factor pathway and was recently introduced as a therapy for advanced HCC. Furthermore, studies have shown that oral sorafenib has beneficial effects on survival. However, many patients experience diverse side effects, and some of these are severe. Liver abscess development has not been previously documented to be associated with sorafenib administration in HCC. Here, we report the case of a HCC patient that developed a liver abscess while being treated with sorafenib.

    Original languageEnglish
    Pages (from-to)47-50
    Number of pages4
    JournalThe Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
    Issue number1
    Publication statusPublished - 2014 Jan 25

    ASJC Scopus subject areas

    • General Medicine


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