Lock release lithography for 3D and composite microparticles

Ki Wan Bong, Daniel C. Pregibon, Patrick S. Doyle

Research output: Contribution to journalArticlepeer-review

76 Citations (Scopus)


We present a method called "Lock Release Lithography (LRL)" that utilizes a combination of channel topography, mask design, and pressure-induced channel deformation to form and release particles in a cycled fashion. This technique provides a means for the high-throughput production of particles with complex 3D morphologies and composite particles with spatially configurable chemistries. In this work, we demonstrate a diverse set of functional particles including those displaying heterogeneous swelling characteristics and containing functional entities such as nucleic acids, proteins and beads.

Original languageEnglish
Pages (from-to)863-866
Number of pages4
JournalLab on a Chip
Issue number7
Publication statusPublished - 2009
Externally publishedYes

ASJC Scopus subject areas

  • Bioengineering
  • Biochemistry
  • Chemistry(all)
  • Biomedical Engineering


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