Longitudinal Deep-Brain Imaging through an Intact Skull Using a Label-Free Reflection Matrix Microscopy

Yongwoo Kwon, Seokchan Yoon, Jin Hee Hong, Hojun Lee, Wonshik Choi

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    We implemented a label-free reflection matrix microscopy system using a 1.3-μm wavelength pulsed laser and conducted in vivo imaging of a 3- to 10-week-old mouse brain with an intact skull. The myelination processes at the early developmental stages were observed up to the cortical layer IV with the ideal diffraction-limited resolution of 650 nm.

    Original languageEnglish
    Title of host publicationCLEO
    Subtitle of host publicationApplications and Technology, A and T 2022
    PublisherOptica Publishing Group (formerly OSA)
    ISBN (Electronic)9781957171050
    Publication statusPublished - 2022
    EventCLEO: Applications and Technology, A and T 2022 - San Jose, United States
    Duration: 2022 May 152022 May 20

    Publication series

    NameOptics InfoBase Conference Papers
    ISSN (Electronic)2162-2701

    Conference

    ConferenceCLEO: Applications and Technology, A and T 2022
    Country/TerritoryUnited States
    CitySan Jose
    Period22/5/1522/5/20

    Bibliographical note

    Publisher Copyright:
    © Optica Publishing Group 2022, © 2022 The Author(s)

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Mechanics of Materials

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