Longitudinal Deep-Brain Imaging through an Intact Skull Using a Label-Free Reflection Matrix Microscopy

Yongwoo Kwon, Seokchan Yoon, Jin Hee Hong, Hojun Lee, Wonshik Choi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We implemented a label-free reflection matrix microscopy system using a 1.3-μm wavelength pulsed laser and conducted in vivo imaging of a 3- to 10-week-old mouse brain with an intact skull. The myelination processes at the early developmental stages were observed up to the cortical layer IV with the ideal diffraction-limited resolution of 650 nm.

Original languageEnglish
Title of host publication2022 Conference on Lasers and Electro-Optics, CLEO 2022 - Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781957171050
Publication statusPublished - 2022
Event2022 Conference on Lasers and Electro-Optics, CLEO 2022 - San Jose, United States
Duration: 2022 May 152022 May 20

Publication series

Name2022 Conference on Lasers and Electro-Optics, CLEO 2022 - Proceedings

Conference

Conference2022 Conference on Lasers and Electro-Optics, CLEO 2022
Country/TerritoryUnited States
CitySan Jose
Period22/5/1522/5/20

Bibliographical note

Publisher Copyright:
© Optica Publishing Group 2022, © 2022 The Author(s)

ASJC Scopus subject areas

  • Instrumentation
  • Spectroscopy
  • Biomedical Engineering
  • Electrical and Electronic Engineering
  • Management, Monitoring, Policy and Law
  • Materials Science (miscellaneous)
  • Acoustics and Ultrasonics
  • Atomic and Molecular Physics, and Optics

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