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Longitudinal Deep-Brain Imaging through an Intact Skull Using a Label-Free Reflection Matrix Microscopy

  • Yongwoo Kwon
  • , Seokchan Yoon
  • , Jin Hee Hong
  • , Hojun Lee
  • , Wonshik Choi*
  • *Corresponding author for this work

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    We implemented a label-free reflection matrix microscopy system using a 1.3-μm wavelength pulsed laser and conducted in vivo imaging of a 3- to 10-week-old mouse brain with an intact skull. The myelination processes at the early developmental stages were observed up to the cortical layer IV with the ideal diffraction-limited resolution of 650 nm.

    Original languageEnglish
    Title of host publication2022 Conference on Lasers and Electro-Optics, CLEO 2022 - Proceedings
    PublisherInstitute of Electrical and Electronics Engineers Inc.
    ISBN (Electronic)9781957171050
    Publication statusPublished - 2022
    Event2022 Conference on Lasers and Electro-Optics, CLEO 2022 - San Jose, United States
    Duration: 2022 May 152022 May 20

    Publication series

    Name2022 Conference on Lasers and Electro-Optics, CLEO 2022 - Proceedings

    Conference

    Conference2022 Conference on Lasers and Electro-Optics, CLEO 2022
    Country/TerritoryUnited States
    CitySan Jose
    Period22/5/1522/5/20

    Bibliographical note

    Publisher Copyright:
    © Optica Publishing Group 2022, © 2022 The Author(s)

    ASJC Scopus subject areas

    • Instrumentation
    • Spectroscopy
    • Biomedical Engineering
    • Electrical and Electronic Engineering
    • Management, Monitoring, Policy and Law
    • Materials Science (miscellaneous)
    • Acoustics and Ultrasonics
    • Atomic and Molecular Physics, and Optics

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