Macroamylasemia in a patient with acute appendicitis: A case report

Jun Won Um; Kwang Hee Kim; Min Seung Kang; Jeong Hoon Choe; Jeoung Won Bae; Yun Sik Hong; Sung Ock Suh; Young Chul Kim; Cheung Wung Whang; Sae Min Kim

doi:10.3346/jkms.1999.14.6.679

Macroamylasemia in a patient with acute appendicitis: A case report

Jun Won Um, Kwang Hee Kim, Min Seung Kang, Jeong Hoon Choe, Jeoung Won Bae, Yun Sik Hong, Sung Ock Suh, Young Chul Kim, Cheung Wung Whang, Sae Min Kim

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

Macroamylasemia is a condition of persistent, elevated serum amylase activity with no apparent clinical symptoms of a pancreatic disorder. In Korea, however, no such case has been reported to date. We report a case of a 17-year-old female diagnosed with macroamylasemia and acute appendicitis. One day earlier, she developed epigastric and right lower quadrant abdominal pain. She was characterized by high level of serum amylase, but normal lipase. Amylase isoenzyme analysis demonstrated increased fraction of salivary type and follow-up amylase level was persistently increased. Immunofixation disclosed the macroamylase binding with an immunoglobulin, consisting of IgA and kappa chain. The patient was treated by appendectomy, and the abdominal pain subsided.

Original language	English
Pages (from-to)	679-681
Number of pages	3
Journal	Journal of Korean medical science
Volume	14
Issue number	6
DOIs	https://doi.org/10.3346/jkms.1999.14.6.679
Publication status	Published - 1999 Dec
Externally published	Yes

Keywords

Amylases
Appendicitis

ASJC Scopus subject areas

General Medicine

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10.3346/jkms.1999.14.6.679

Cite this

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title = "Macroamylasemia in a patient with acute appendicitis: A case report",

abstract = "Macroamylasemia is a condition of persistent, elevated serum amylase activity with no apparent clinical symptoms of a pancreatic disorder. In Korea, however, no such case has been reported to date. We report a case of a 17-year-old female diagnosed with macroamylasemia and acute appendicitis. One day earlier, she developed epigastric and right lower quadrant abdominal pain. She was characterized by high level of serum amylase, but normal lipase. Amylase isoenzyme analysis demonstrated increased fraction of salivary type and follow-up amylase level was persistently increased. Immunofixation disclosed the macroamylase binding with an immunoglobulin, consisting of IgA and kappa chain. The patient was treated by appendectomy, and the abdominal pain subsided.",

keywords = "Amylases, Appendicitis",

author = "Um, {Jun Won} and Kim, {Kwang Hee} and Kang, {Min Seung} and Choe, {Jeong Hoon} and Bae, {Jeoung Won} and Hong, {Yun Sik} and Suh, {Sung Ock} and Kim, {Young Chul} and Whang, {Cheung Wung} and Kim, {Sae Min}",

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T2 - A case report

AU - Um, Jun Won

AU - Kim, Kwang Hee

AU - Kang, Min Seung

AU - Choe, Jeong Hoon

AU - Bae, Jeoung Won

AU - Hong, Yun Sik

AU - Suh, Sung Ock

AU - Kim, Young Chul

AU - Whang, Cheung Wung

AU - Kim, Sae Min

PY - 1999/12

Y1 - 1999/12

N2 - Macroamylasemia is a condition of persistent, elevated serum amylase activity with no apparent clinical symptoms of a pancreatic disorder. In Korea, however, no such case has been reported to date. We report a case of a 17-year-old female diagnosed with macroamylasemia and acute appendicitis. One day earlier, she developed epigastric and right lower quadrant abdominal pain. She was characterized by high level of serum amylase, but normal lipase. Amylase isoenzyme analysis demonstrated increased fraction of salivary type and follow-up amylase level was persistently increased. Immunofixation disclosed the macroamylase binding with an immunoglobulin, consisting of IgA and kappa chain. The patient was treated by appendectomy, and the abdominal pain subsided.

AB - Macroamylasemia is a condition of persistent, elevated serum amylase activity with no apparent clinical symptoms of a pancreatic disorder. In Korea, however, no such case has been reported to date. We report a case of a 17-year-old female diagnosed with macroamylasemia and acute appendicitis. One day earlier, she developed epigastric and right lower quadrant abdominal pain. She was characterized by high level of serum amylase, but normal lipase. Amylase isoenzyme analysis demonstrated increased fraction of salivary type and follow-up amylase level was persistently increased. Immunofixation disclosed the macroamylase binding with an immunoglobulin, consisting of IgA and kappa chain. The patient was treated by appendectomy, and the abdominal pain subsided.

KW - Amylases

KW - Appendicitis

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IS - 6

ER -

Macroamylasemia in a patient with acute appendicitis: A case report

Abstract

Keywords

ASJC Scopus subject areas

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