Abstract
Magnetic particle imaging (MPI) is a novel high-resolution medical imaging method that does not use ionizing radiation, but safe iron oxide nanoparticles as contrast agents. By employing magnetite (Fe3O4) multi-granule nanoclusters (MGNCs), one has two control parameters: the diameter of the particles and that of granules in single particles. Here we investigate the effect of the size of the particles at constant granule size, as well as the effect of granule size at constant particle size on the magnetization reversal. The saturation magnetization Ms value increases with increasing granule diameter and particle diameter, while the coercivity Hc value reaches a maximum at a particle size of about 60 nm. MGNCs with an average particle size of 77 nm and granule diameter of 17 nm show a larger response in the higher harmonics compared to the commercial reference, FeraSpin R dispersion, at both 20 and 30 mT. This result demonstrates that the MGNC concept allows tailoring of the magnetic properties of the particles to the imaging conditions in MPI.
Original language | English |
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Article number | 7921601 |
Journal | IEEE Transactions on Magnetics |
Volume | 53 |
Issue number | 11 |
DOIs | |
Publication status | Published - 2017 Nov |
Bibliographical note
Funding Information:ACKNOWLEDGMENT This research was supported by the National Research Foundation of Korea under Grant 2014M3A7B4052193 and Grant 2015R1A2A1A15053002.
Publisher Copyright:
© 2017 IEEE.
Keywords
- FeO
- magnetic particle spectrometry
- magnetic properties
- multi-granule nanoclusters (MGNCs)
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Electrical and Electronic Engineering