Magnetic sensitivity enhanced novel fluorescent magnetic silica nanoparticles for biomedical applications

Jaemoon Yang; Jaewon Lee; Jinyoung Kang; Chan Hwa Chung; Kwangyeol Lee; Jin Suck Suh; Ho Geun Yoon; Yong Min Huh; Seungjoo Haam

doi:10.1088/0957-4484/19/7/075610

Magnetic sensitivity enhanced novel fluorescent magnetic silica nanoparticles for biomedical applications

Jaemoon Yang, Jaewon Lee, Jinyoung Kang, Chan Hwa Chung, Kwangyeol Lee, Jin Suck Suh, Ho Geun Yoon, Yong Min Huh, Seungjoo Haam

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

We synthesized novel fluorescent magnetic silica nanoparticles (FMSNPs) containing large magnetic components for biomedical application. By employing assemblies of magnetic nanoparticles as kernels against FMSNPs, both the saturation of magnetization and the magnetic resonance (MR) signal intensity were significantly enhanced. Furthermore, the cellular binding of FMSNPs was improved by introducing a positive charge on the surface of the FMSNPs, and fluorescent dyes on the surface of FMSNPs enable optical imaging of sub-cellular regions.

Original language	English
Article number	075610
Journal	Nanotechnology
Volume	19
Issue number	7
DOIs	https://doi.org/10.1088/0957-4484/19/7/075610
Publication status	Published - 2008

ASJC Scopus subject areas

Bioengineering
Chemistry(all)
Materials Science(all)
Mechanics of Materials
Mechanical Engineering
Electrical and Electronic Engineering

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abstract = "We synthesized novel fluorescent magnetic silica nanoparticles (FMSNPs) containing large magnetic components for biomedical application. By employing assemblies of magnetic nanoparticles as kernels against FMSNPs, both the saturation of magnetization and the magnetic resonance (MR) signal intensity were significantly enhanced. Furthermore, the cellular binding of FMSNPs was improved by introducing a positive charge on the surface of the FMSNPs, and fluorescent dyes on the surface of FMSNPs enable optical imaging of sub-cellular regions.",

author = "Jaemoon Yang and Jaewon Lee and Jinyoung Kang and Chung, {Chan Hwa} and Kwangyeol Lee and Suh, {Jin Suck} and Yoon, {Ho Geun} and Huh, {Yong Min} and Seungjoo Haam",

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T1 - Magnetic sensitivity enhanced novel fluorescent magnetic silica nanoparticles for biomedical applications

AU - Yang, Jaemoon

AU - Lee, Jaewon

AU - Kang, Jinyoung

AU - Chung, Chan Hwa

AU - Lee, Kwangyeol

AU - Suh, Jin Suck

AU - Yoon, Ho Geun

AU - Huh, Yong Min

AU - Haam, Seungjoo

PY - 2008

Y1 - 2008

N2 - We synthesized novel fluorescent magnetic silica nanoparticles (FMSNPs) containing large magnetic components for biomedical application. By employing assemblies of magnetic nanoparticles as kernels against FMSNPs, both the saturation of magnetization and the magnetic resonance (MR) signal intensity were significantly enhanced. Furthermore, the cellular binding of FMSNPs was improved by introducing a positive charge on the surface of the FMSNPs, and fluorescent dyes on the surface of FMSNPs enable optical imaging of sub-cellular regions.

AB - We synthesized novel fluorescent magnetic silica nanoparticles (FMSNPs) containing large magnetic components for biomedical application. By employing assemblies of magnetic nanoparticles as kernels against FMSNPs, both the saturation of magnetization and the magnetic resonance (MR) signal intensity were significantly enhanced. Furthermore, the cellular binding of FMSNPs was improved by introducing a positive charge on the surface of the FMSNPs, and fluorescent dyes on the surface of FMSNPs enable optical imaging of sub-cellular regions.

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U2 - 10.1088/0957-4484/19/7/075610

DO - 10.1088/0957-4484/19/7/075610

M3 - Article

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SN - 0957-4484

VL - 19

JO - Nanotechnology

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M1 - 075610

ER -

Magnetic sensitivity enhanced novel fluorescent magnetic silica nanoparticles for biomedical applications

Abstract

ASJC Scopus subject areas

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