Magnetic sensitivity enhanced novel fluorescent magnetic silica nanoparticles for biomedical applications

Jaemoon Yang, Jaewon Lee, Jinyoung Kang, Chan Hwa Chung, Kwangyeol Lee, Jin Suck Suh, Ho Geun Yoon, Yong Min Huh, Seungjoo Haam

    Research output: Contribution to journalArticlepeer-review

    25 Citations (Scopus)

    Abstract

    We synthesized novel fluorescent magnetic silica nanoparticles (FMSNPs) containing large magnetic components for biomedical application. By employing assemblies of magnetic nanoparticles as kernels against FMSNPs, both the saturation of magnetization and the magnetic resonance (MR) signal intensity were significantly enhanced. Furthermore, the cellular binding of FMSNPs was improved by introducing a positive charge on the surface of the FMSNPs, and fluorescent dyes on the surface of FMSNPs enable optical imaging of sub-cellular regions.

    Original languageEnglish
    Article number075610
    JournalNanotechnology
    Volume19
    Issue number7
    DOIs
    Publication statusPublished - 2008

    ASJC Scopus subject areas

    • Bioengineering
    • General Chemistry
    • General Materials Science
    • Mechanics of Materials
    • Mechanical Engineering
    • Electrical and Electronic Engineering

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