MeCP2 Caught Moonlighting as a Suppressor of MicroRNA Processing

Jae Sung Woo; V. Narry Kim

doi:10.1016/j.devcel.2014.02.015

MeCP2 Caught Moonlighting as a Suppressor of MicroRNA Processing

Jae Sung Woo, V. Narry Kim

Research output: Contribution to journal › Short survey › peer-review

7 Citations (Scopus)

Abstract

MeCP2 is a transcriptional regulator important for neurodevelopment and is involved in Rett syndrome and autism. In this issue of Developmental Cell, Cheng and colleagues (2014) report that MeCP2 also regulates microRNA biogenesis. MeCP2 phosphorylation induces a direct interaction with DGCR8, leading to reduced microRNA processing and retardation of dendritic growth.

Original language	English
Pages (from-to)	477-478
Number of pages	2
Journal	Developmental Cell
Volume	28
Issue number	5
DOIs	https://doi.org/10.1016/j.devcel.2014.02.015
Publication status	Published - 2014 Mar 10
Externally published	Yes

ASJC Scopus subject areas

Molecular Biology
Biochemistry, Genetics and Molecular Biology(all)
Developmental Biology
Cell Biology

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10.1016/j.devcel.2014.02.015

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title = "MeCP2 Caught Moonlighting as a Suppressor of MicroRNA Processing",

abstract = "MeCP2 is a transcriptional regulator important for neurodevelopment and is involved in Rett syndrome and autism. In this issue of Developmental Cell, Cheng and colleagues (2014) report that MeCP2 also regulates microRNA biogenesis. MeCP2 phosphorylation induces a direct interaction with DGCR8, leading to reduced microRNA processing and retardation of dendritic growth.",

author = "Woo, {Jae Sung} and Kim, {V. Narry}",

year = "2014",

month = mar,

day = "10",

doi = "10.1016/j.devcel.2014.02.015",

language = "English",

volume = "28",

pages = "477--478",

journal = "Developmental Cell",

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T1 - MeCP2 Caught Moonlighting as a Suppressor of MicroRNA Processing

AU - Woo, Jae Sung

AU - Kim, V. Narry

PY - 2014/3/10

Y1 - 2014/3/10

N2 - MeCP2 is a transcriptional regulator important for neurodevelopment and is involved in Rett syndrome and autism. In this issue of Developmental Cell, Cheng and colleagues (2014) report that MeCP2 also regulates microRNA biogenesis. MeCP2 phosphorylation induces a direct interaction with DGCR8, leading to reduced microRNA processing and retardation of dendritic growth.

AB - MeCP2 is a transcriptional regulator important for neurodevelopment and is involved in Rett syndrome and autism. In this issue of Developmental Cell, Cheng and colleagues (2014) report that MeCP2 also regulates microRNA biogenesis. MeCP2 phosphorylation induces a direct interaction with DGCR8, leading to reduced microRNA processing and retardation of dendritic growth.

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U2 - 10.1016/j.devcel.2014.02.015

DO - 10.1016/j.devcel.2014.02.015

M3 - Short survey

C2 - 24636253

AN - SCOPUS:84895761370

SN - 1534-5807

VL - 28

SP - 477

EP - 478

JO - Developmental Cell

JF - Developmental Cell

IS - 5

ER -

MeCP2 Caught Moonlighting as a Suppressor of MicroRNA Processing

Abstract

ASJC Scopus subject areas

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