Metabolic engineering of solventogenic clostridia for butanol production

Sang Hyun Lee, Kyoung Heon Kim

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Abstract

    Butanol can be produced by fermentation using solventogenic clostridia. However, economical production of butanol is hampered due to low fermentation efficiency and high substrate costs. To overcome these problems, genetic manipulations have been widely applied to solventogenic clostridia on the basis of systems metabolic engineering. This review mainly discusses the recent advances in strain development and improvements in fermentation performance.

    Original languageEnglish
    Title of host publicationEmerging Areas in Bioengineering
    Publisherwiley
    Pages331-348
    Number of pages18
    ISBN (Electronic)9783527803286
    ISBN (Print)9783527340880
    DOIs
    Publication statusPublished - 2017 Jan 1

    Bibliographical note

    Publisher Copyright:
    © 2018Wiley-VCH Verlag GmbH & Co. KGaA. Published 2018 byWiley-VCH Verlag GmbH & Co. KGaA.

    Keywords

    • Butanol
    • Fermentation
    • Metabolic engineering
    • Solventogenic clostridia

    ASJC Scopus subject areas

    • General Biochemistry,Genetics and Molecular Biology

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