Metal ion-induced FRET modulation in a bifluorophore system

Su Yeon Lee; Hyun Jung Kim; Jia Sheng Wu; Kwanghyun No; Jong Seung Kim

doi:10.1016/j.tetlet.2008.08.027

Metal ion-induced FRET modulation in a bifluorophore system

Su Yeon Lee, Hyun Jung Kim, Jia Sheng Wu, Kwanghyun No, Jong Seung Kim

Research output: Contribution to journal › Article › peer-review

27 Citations (Scopus)

Abstract

A new fluorogenic sensor 1 capable of illustrating metal ion-triggered FRET changes has been synthesized. Based on the FRET changes, 1, bearing coumarin-fluorescein moieties, provides a selective sensor for Cu²⁺ and Hg²⁺ ions for experiments implemented in aqueous media with a chloride counter anion.

Original language	English
Pages (from-to)	6141-6144
Number of pages	4
Journal	Tetrahedron Letters
Volume	49
Issue number	42
DOIs	https://doi.org/10.1016/j.tetlet.2008.08.027
Publication status	Published - 2008 Oct 13

Bibliographical note

Funding Information:
The authors wish to acknowledge the financial support of the SRC program (R11-2005-008-02001-0(2008) and the SRC Research Centre for Women’s Diseases of Sookmyung Women’s University.

Keywords

FRET
Fluorescence
Heavy metal ion effect

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tetlet.2008.08.027

Cite this

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title = "Metal ion-induced FRET modulation in a bifluorophore system",

abstract = "A new fluorogenic sensor 1 capable of illustrating metal ion-triggered FRET changes has been synthesized. Based on the FRET changes, 1, bearing coumarin-fluorescein moieties, provides a selective sensor for Cu2+ and Hg2+ ions for experiments implemented in aqueous media with a chloride counter anion.",

keywords = "FRET, Fluorescence, Heavy metal ion effect",

author = "Lee, {Su Yeon} and Kim, {Hyun Jung} and Wu, {Jia Sheng} and Kwanghyun No and Kim, {Jong Seung}",

note = "Funding Information: The authors wish to acknowledge the financial support of the SRC program (R11-2005-008-02001-0(2008) and the SRC Research Centre for Women{\textquoteright}s Diseases of Sookmyung Women{\textquoteright}s University. ",

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month = oct,

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doi = "10.1016/j.tetlet.2008.08.027",

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journal = "Tetrahedron Letters",

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AU - Lee, Su Yeon

AU - Kim, Hyun Jung

AU - Wu, Jia Sheng

AU - No, Kwanghyun

AU - Kim, Jong Seung

N1 - Funding Information: The authors wish to acknowledge the financial support of the SRC program (R11-2005-008-02001-0(2008) and the SRC Research Centre for Women’s Diseases of Sookmyung Women’s University.

PY - 2008/10/13

Y1 - 2008/10/13

N2 - A new fluorogenic sensor 1 capable of illustrating metal ion-triggered FRET changes has been synthesized. Based on the FRET changes, 1, bearing coumarin-fluorescein moieties, provides a selective sensor for Cu2+ and Hg2+ ions for experiments implemented in aqueous media with a chloride counter anion.

AB - A new fluorogenic sensor 1 capable of illustrating metal ion-triggered FRET changes has been synthesized. Based on the FRET changes, 1, bearing coumarin-fluorescein moieties, provides a selective sensor for Cu2+ and Hg2+ ions for experiments implemented in aqueous media with a chloride counter anion.

KW - FRET

KW - Fluorescence

KW - Heavy metal ion effect

UR - http://www.scopus.com/inward/record.url?scp=50549101913&partnerID=8YFLogxK

U2 - 10.1016/j.tetlet.2008.08.027

DO - 10.1016/j.tetlet.2008.08.027

M3 - Article

AN - SCOPUS:50549101913

SN - 0040-4039

VL - 49

SP - 6141

EP - 6144

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 42

ER -

Metal ion-induced FRET modulation in a bifluorophore system

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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