Metal ion-induced FRET modulation in a bifluorophore system

Su Yeon Lee, Hyun Jung Kim, Jia Sheng Wu, Kwanghyun No, Jong Seung Kim

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)


A new fluorogenic sensor 1 capable of illustrating metal ion-triggered FRET changes has been synthesized. Based on the FRET changes, 1, bearing coumarin-fluorescein moieties, provides a selective sensor for Cu2+ and Hg2+ ions for experiments implemented in aqueous media with a chloride counter anion.

Original languageEnglish
Pages (from-to)6141-6144
Number of pages4
JournalTetrahedron Letters
Issue number42
Publication statusPublished - 2008 Oct 13

Bibliographical note

Funding Information:
The authors wish to acknowledge the financial support of the SRC program (R11-2005-008-02001-0(2008) and the SRC Research Centre for Women’s Diseases of Sookmyung Women’s University.


  • FRET
  • Fluorescence
  • Heavy metal ion effect

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


Dive into the research topics of 'Metal ion-induced FRET modulation in a bifluorophore system'. Together they form a unique fingerprint.

Cite this