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Mice deficient in TWIK-1 are more susceptible to kainic acid-induced seizures
Ajung Kim
, Yeonju Bae
, Changdev G. Gadhe
, Hyun Gug Jung
, Esther Yang
,
Hyun Kim
, Jaekwang Lee
, Chanseob Shim
, Young Hoon Sung
, Junyeol Noh
, Eun Jin Kim
, Dawon Kang
, Ae Nim Pae
, Eun Mi Hwang
*
,
Jae Yong Park
*
*
Corresponding author for this work
Department of Biomedical Sciences
School of Biosystem and Biomedical Science
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Keyphrases
Seizure
100%
Acid Activation
100%
Kainic Acid
100%
TWIK-1
100%
Knock-in Mouse Model
33%
Passive Conductance
33%
Physiological Role
22%
Astrocytic
22%
Exon 2
22%
Exon 1
22%
K Channels
11%
K+ Conductance
11%
Astrocytes
11%
Increased Vulnerability
11%
Functional Studies
11%
K+ Current
11%
K2P Channel
11%
Two-pore
11%
Pore Domain
11%
Cas9 Protein
11%
Biochemistry, Genetics and Molecular Biology
Exon
100%
Kainic Acid
100%
Conductance
100%
Knockout Mouse
75%
Potassium Channel
25%
Astrocyte
25%
Potassium Current
25%
CRISPR/Cas9
25%
Neuroscience
Kainic Acid
100%
Exon
100%
Potassium Channel
25%
Astrocyte
25%
Potassium Current
25%
CRISPR
25%