Microencapsulation of insulin microcrystals

Sung Hee Choi, Jai Hyun Kwon, Chan Wha Kim

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)


Insulin microcrystals were encapsulated (microcrystal/PLGA) within poly(lactide-co-glycolide) (PLGA 50:50) by the multiple emulsification solvent evaporation technique and compared with insulin solution microspheres (solution/PLGA) in terms of their morphology, size distribution, drug content, encapsulation efficiency, and stability of insulin during release.

Original languageEnglish
Pages (from-to)749-752
Number of pages4
JournalBioscience, Biotechnology and Biochemistry
Issue number3
Publication statusPublished - 2004 Mar

Bibliographical note

Funding Information:
This work was financially supported by the Korean Ministry of Commerce, Industry, and Energy as an industrial and technological development project. Sung Hee Choi and Jai-Hyun Kwon have each been awarded a Brain Korea 21 fellowship from the Korean Ministry of Education & Human Resources Development.


  • Insulin
  • Microcrystal
  • Microsphere
  • Poly (lactide-co-glycolide) (PLGA)
  • Stability

ASJC Scopus subject areas

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry


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