Microfluidic chip-type electrochemical immunoassay for hippuric acid

Sung Ju Yoo, Young Bong Choi, Jongil Ju, Gun Sik Tae, Hyug Han Kim, Sang Hoon Lee

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We describe a simple method for rapid and quantitative detection of hippuric acid (HA) by using PDMS-based microfluidic electrochemical immunosensor. The system employs a conjugate of ferrocene (Fc) and HA for the electrochemical detection. The competition between HA and the ferrocene-hippuric acid complex (Fc-Lys-HA) for HA antibody coated onto microbeads generates electrical signals proportional to HA concentration in the range of 0-40 mg/mL.

Original languageEnglish
Title of host publicationProceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages308-310
Number of pages3
ISBN (Print)9780979806421
Publication statusPublished - 2009
Event13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009 - Jeju, Korea, Republic of
Duration: 2009 Nov 12009 Nov 5

Publication series

NameProceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Other

Other13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009
Country/TerritoryKorea, Republic of
CityJeju
Period09/11/109/11/5

Keywords

  • Electrochemical immunosensor
  • Hippuric acid
  • Microfluidic chip
  • Small antigen

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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