Microfluidic spinning of flat alginate fibers with grooves for cell-aligning scaffolds

Edward Kang; Yoon Young Choi; Su Kyoung Chae; Jin Hee Moon; Joon Young Chang; Sang Hoon Lee

doi:10.1002/adma.201201232

Microfluidic spinning of flat alginate fibers with grooves for cell-aligning scaffolds

Edward Kang, Yoon Young Choi, Su Kyoung Chae, Jin Hee Moon, Joon Young Chang, Sang Hoon Lee

Department of Bio-convergence Engineering

Research output: Contribution to journal › Article › peer-review

211 Citations (Scopus)

Abstract

Alginate microribbons with longitudinally grooved microstructures are continuously fabricated by means of a microfluidic system. The number and dimensions of the microgroovesare successfully controlled by regulation of the slit-shaped channel (yellow in figure). This method opens up the possibility of mass production of scaffolds for tissue engineering purposes, as it is proved that the grooved flat fibers can be used to align other types of cells in culture.

Original language	English
Pages (from-to)	4271-4277
Number of pages	7
Journal	Advanced Materials
Volume	24
Issue number	31
DOIs	https://doi.org/10.1002/adma.201201232
Publication status	Published - 2012 Aug 16

Keywords

alginates
cell alignment
fibers
grooved
microfluidic spinning
microstructures
patterned
ribbons

ASJC Scopus subject areas

Materials Science(all)
Mechanics of Materials
Mechanical Engineering

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10.1002/adma.201201232

Cite this

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title = "Microfluidic spinning of flat alginate fibers with grooves for cell-aligning scaffolds",

abstract = "Alginate microribbons with longitudinally grooved microstructures are continuously fabricated by means of a microfluidic system. The number and dimensions of the microgroovesare successfully controlled by regulation of the slit-shaped channel (yellow in figure). This method opens up the possibility of mass production of scaffolds for tissue engineering purposes, as it is proved that the grooved flat fibers can be used to align other types of cells in culture.",

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author = "Edward Kang and Choi, {Yoon Young} and Chae, {Su Kyoung} and Moon, {Jin Hee} and Chang, {Joon Young} and Lee, {Sang Hoon}",

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AU - Kang, Edward

AU - Choi, Yoon Young

AU - Chae, Su Kyoung

AU - Moon, Jin Hee

AU - Chang, Joon Young

AU - Lee, Sang Hoon

PY - 2012/8/16

Y1 - 2012/8/16

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AB - Alginate microribbons with longitudinally grooved microstructures are continuously fabricated by means of a microfluidic system. The number and dimensions of the microgroovesare successfully controlled by regulation of the slit-shaped channel (yellow in figure). This method opens up the possibility of mass production of scaffolds for tissue engineering purposes, as it is proved that the grooved flat fibers can be used to align other types of cells in culture.

KW - alginates

KW - cell alignment

KW - fibers

KW - grooved

KW - microfluidic spinning

KW - microstructures

KW - patterned

KW - ribbons

UR - http://www.scopus.com/inward/record.url?scp=84864678930&partnerID=8YFLogxK

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EP - 4277

JO - Advanced Materials

JF - Advanced Materials

IS - 31

ER -

Microfluidic spinning of flat alginate fibers with grooves for cell-aligning scaffolds

Abstract

Keywords

ASJC Scopus subject areas

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