Microfluidic spinning of flat alginate fibers with grooves for cell-aligning scaffolds

Edward Kang, Yoon Young Choi, Su Kyoung Chae, Jin Hee Moon, Joon Young Chang, Sang Hoon Lee

Research output: Contribution to journalArticlepeer-review

218 Citations (Scopus)


Alginate microribbons with longitudinally grooved microstructures are continuously fabricated by means of a microfluidic system. The number and dimensions of the microgroovesare successfully controlled by regulation of the slit-shaped channel (yellow in figure). This method opens up the possibility of mass production of scaffolds for tissue engineering purposes, as it is proved that the grooved flat fibers can be used to align other types of cells in culture.

Original languageEnglish
Pages (from-to)4271-4277
Number of pages7
JournalAdvanced Materials
Issue number31
Publication statusPublished - 2012 Aug 16


  • alginates
  • cell alignment
  • fibers
  • grooved
  • microfluidic spinning
  • microstructures
  • patterned
  • ribbons

ASJC Scopus subject areas

  • General Materials Science
  • Mechanics of Materials
  • Mechanical Engineering


Dive into the research topics of 'Microfluidic spinning of flat alginate fibers with grooves for cell-aligning scaffolds'. Together they form a unique fingerprint.

Cite this