We report the precise decoding of a shape-modulated hydrogel barcode particle using a micropore fluidic device. Using an electrical simulation, we deduced the optimal pore geometry that yields the maximal sensing signal. We fabricated hydrogel particles with different dimensions and prepared the micropore device along with a fluidic cell and a patch clamp. Accordingly, we experimentally determined the most appropriate shape of the hydrogel barcode particle that allows efficient differentiation between a 0 code and a 1 code. Thus, we successfully decoded 4-bit hydrogel barcode particles with high speed and high accuracy.
Bibliographical noteFunding Information:
This work was supported by the Engineering Research Center of Excellence Program ( NRF-2016R1A5A1010148 ) and the Basic Science Research Program through the National Research Foundation of Korea (NRF) (grant numbers 2018R1D1A1B07046577 and 2018R1A2A1A05023556 ).
© 2019 Elsevier B.V.
- Hydrogel barcode particle
- Low-aspect-ratio micropore sensor
- Multiplexed detection
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Surfaces, Coatings and Films
- Metals and Alloys
- Electrical and Electronic Engineering
- Materials Chemistry