Micropore device for identification of 4-bit hydrogel barcode

Jihun Ryu; Hyeon Ung Kim; Chang Woo Song; Sehyun Shin; Ki Wan Bong; Chang Soo Han

doi:10.1016/j.snb.2019.127622

Micropore device for identification of 4-bit hydrogel barcode

Jihun Ryu, Hyeon Ung Kim, Chang Woo Song, Sehyun Shin, Ki Wan Bong, Chang Soo Han

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

We report the precise decoding of a shape-modulated hydrogel barcode particle using a micropore fluidic device. Using an electrical simulation, we deduced the optimal pore geometry that yields the maximal sensing signal. We fabricated hydrogel particles with different dimensions and prepared the micropore device along with a fluidic cell and a patch clamp. Accordingly, we experimentally determined the most appropriate shape of the hydrogel barcode particle that allows efficient differentiation between a 0 code and a 1 code. Thus, we successfully decoded 4-bit hydrogel barcode particles with high speed and high accuracy.

Original language	English
Article number	127622
Journal	Sensors and Actuators, B: Chemical
Volume	307
DOIs	https://doi.org/10.1016/j.snb.2019.127622
Publication status	Published - 2020 Mar 15

Bibliographical note

Funding Information:
This work was supported by the Engineering Research Center of Excellence Program ( NRF-2016R1A5A1010148 ) and the Basic Science Research Program through the National Research Foundation of Korea (NRF) (grant numbers 2018R1D1A1B07046577 and 2018R1A2A1A05023556 ).

Publisher Copyright:
© 2019 Elsevier B.V.

Keywords

Hydrogel barcode particle
Low-aspect-ratio micropore sensor
Multiplexed detection

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Instrumentation
Condensed Matter Physics
Surfaces, Coatings and Films
Metals and Alloys
Electrical and Electronic Engineering
Materials Chemistry

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10.1016/j.snb.2019.127622

Cite this

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title = "Micropore device for identification of 4-bit hydrogel barcode",

abstract = "We report the precise decoding of a shape-modulated hydrogel barcode particle using a micropore fluidic device. Using an electrical simulation, we deduced the optimal pore geometry that yields the maximal sensing signal. We fabricated hydrogel particles with different dimensions and prepared the micropore device along with a fluidic cell and a patch clamp. Accordingly, we experimentally determined the most appropriate shape of the hydrogel barcode particle that allows efficient differentiation between a 0 code and a 1 code. Thus, we successfully decoded 4-bit hydrogel barcode particles with high speed and high accuracy.",

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AU - Kim, Hyeon Ung

AU - Song, Chang Woo

AU - Shin, Sehyun

AU - Bong, Ki Wan

AU - Han, Chang Soo

N1 - Funding Information: This work was supported by the Engineering Research Center of Excellence Program ( NRF-2016R1A5A1010148 ) and the Basic Science Research Program through the National Research Foundation of Korea (NRF) (grant numbers 2018R1D1A1B07046577 and 2018R1A2A1A05023556 ). Publisher Copyright: © 2019 Elsevier B.V.

PY - 2020/3/15

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N2 - We report the precise decoding of a shape-modulated hydrogel barcode particle using a micropore fluidic device. Using an electrical simulation, we deduced the optimal pore geometry that yields the maximal sensing signal. We fabricated hydrogel particles with different dimensions and prepared the micropore device along with a fluidic cell and a patch clamp. Accordingly, we experimentally determined the most appropriate shape of the hydrogel barcode particle that allows efficient differentiation between a 0 code and a 1 code. Thus, we successfully decoded 4-bit hydrogel barcode particles with high speed and high accuracy.

AB - We report the precise decoding of a shape-modulated hydrogel barcode particle using a micropore fluidic device. Using an electrical simulation, we deduced the optimal pore geometry that yields the maximal sensing signal. We fabricated hydrogel particles with different dimensions and prepared the micropore device along with a fluidic cell and a patch clamp. Accordingly, we experimentally determined the most appropriate shape of the hydrogel barcode particle that allows efficient differentiation between a 0 code and a 1 code. Thus, we successfully decoded 4-bit hydrogel barcode particles with high speed and high accuracy.

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KW - Multiplexed detection

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Micropore device for identification of 4-bit hydrogel barcode

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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