Abstract
An ultrasensitive nanogap junction is developed for label-free biomolecular detection. The nanogap junction can minimize the effects of electrode polarization. Without any label, dielectric detection of DNA hybridization is accomplished: the 70% and 12% changes of capacitance after hybridization were accomplished at 100 Hz for 10 μM and 10 fM concentrations of target DNA, respectively. The nanogap junction-based dielectric DNA detection method and the batch fabrication method of nanogap junctions might able to change the paradigm of functional genomics and proteomics.
Original language | English |
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Title of host publication | 2002 International Microprocesses and Nanotechnology Conference, MNC 2002 |
Publisher | Institute of Electrical and Electronics Engineers Inc. |
Pages | 286-287 |
Number of pages | 2 |
ISBN (Electronic) | 4891140313, 9784891140311 |
DOIs | |
Publication status | Published - 2002 |
Externally published | Yes |
Event | International Microprocesses and Nanotechnology Conference, MNC 2002 - Tokyo, Japan Duration: 2002 Nov 6 → 2002 Nov 8 |
Other
Other | International Microprocesses and Nanotechnology Conference, MNC 2002 |
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Country/Territory | Japan |
City | Tokyo |
Period | 02/11/6 → 02/11/8 |
ASJC Scopus subject areas
- Hardware and Architecture
- Electrical and Electronic Engineering