Molecular nanoelectronics for label free DNA analysis

L. P. Lee; S. Oh; Yeonho Choi; J. S. Lee

doi:10.1109/IMNC.2002.1178655

Molecular nanoelectronics for label free DNA analysis

L. P. Lee, S. Oh, Yeonho Choi, J. S. Lee

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Citation (Scopus)

Abstract

An ultrasensitive nanogap junction is developed for label-free biomolecular detection. The nanogap junction can minimize the effects of electrode polarization. Without any label, dielectric detection of DNA hybridization is accomplished: the 70% and 12% changes of capacitance after hybridization were accomplished at 100 Hz for 10 μM and 10 fM concentrations of target DNA, respectively. The nanogap junction-based dielectric DNA detection method and the batch fabrication method of nanogap junctions might able to change the paradigm of functional genomics and proteomics.

Original language	English
Title of host publication	2002 International Microprocesses and Nanotechnology Conference, MNC 2002
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	286-287
Number of pages	2
ISBN (Electronic)	4891140313, 9784891140311
DOIs	https://doi.org/10.1109/IMNC.2002.1178655
Publication status	Published - 2002
Externally published	Yes
Event	International Microprocesses and Nanotechnology Conference, MNC 2002 - Tokyo, Japan Duration: 2002 Nov 6 → 2002 Nov 8

Other

Other	International Microprocesses and Nanotechnology Conference, MNC 2002
Country/Territory	Japan
City	Tokyo
Period	02/11/6 → 02/11/8

ASJC Scopus subject areas

Hardware and Architecture
Electrical and Electronic Engineering

Access to Document

10.1109/IMNC.2002.1178655

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Lee, LP, Oh, S, Choi, Y & Lee, JS 2002, Molecular nanoelectronics for label free DNA analysis. in 2002 International Microprocesses and Nanotechnology Conference, MNC 2002., 1178655, Institute of Electrical and Electronics Engineers Inc., pp. 286-287, International Microprocesses and Nanotechnology Conference, MNC 2002, Tokyo, Japan, 02/11/6. https://doi.org/10.1109/IMNC.2002.1178655

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title = "Molecular nanoelectronics for label free DNA analysis",

abstract = "An ultrasensitive nanogap junction is developed for label-free biomolecular detection. The nanogap junction can minimize the effects of electrode polarization. Without any label, dielectric detection of DNA hybridization is accomplished: the 70\% and 12\% changes of capacitance after hybridization were accomplished at 100 Hz for 10 μM and 10 fM concentrations of target DNA, respectively. The nanogap junction-based dielectric DNA detection method and the batch fabrication method of nanogap junctions might able to change the paradigm of functional genomics and proteomics.",

author = "Lee, \{L. P.\} and S. Oh and Yeonho Choi and Lee, \{J. S.\}",

year = "2002",

doi = "10.1109/IMNC.2002.1178655",

language = "English",

pages = "286--287",

booktitle = "2002 International Microprocesses and Nanotechnology Conference, MNC 2002",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

note = "International Microprocesses and Nanotechnology Conference, MNC 2002 ; Conference date: 06-11-2002 Through 08-11-2002",

}

TY - GEN

T1 - Molecular nanoelectronics for label free DNA analysis

AU - Lee, L. P.

AU - Oh, S.

AU - Choi, Yeonho

AU - Lee, J. S.

PY - 2002

Y1 - 2002

N2 - An ultrasensitive nanogap junction is developed for label-free biomolecular detection. The nanogap junction can minimize the effects of electrode polarization. Without any label, dielectric detection of DNA hybridization is accomplished: the 70% and 12% changes of capacitance after hybridization were accomplished at 100 Hz for 10 μM and 10 fM concentrations of target DNA, respectively. The nanogap junction-based dielectric DNA detection method and the batch fabrication method of nanogap junctions might able to change the paradigm of functional genomics and proteomics.

AB - An ultrasensitive nanogap junction is developed for label-free biomolecular detection. The nanogap junction can minimize the effects of electrode polarization. Without any label, dielectric detection of DNA hybridization is accomplished: the 70% and 12% changes of capacitance after hybridization were accomplished at 100 Hz for 10 μM and 10 fM concentrations of target DNA, respectively. The nanogap junction-based dielectric DNA detection method and the batch fabrication method of nanogap junctions might able to change the paradigm of functional genomics and proteomics.

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U2 - 10.1109/IMNC.2002.1178655

DO - 10.1109/IMNC.2002.1178655

M3 - Conference contribution

AN - SCOPUS:84960337801

SP - 286

EP - 287

BT - 2002 International Microprocesses and Nanotechnology Conference, MNC 2002

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - International Microprocesses and Nanotechnology Conference, MNC 2002

Y2 - 6 November 2002 through 8 November 2002

ER -

Molecular nanoelectronics for label free DNA analysis

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