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Molecularly engineered siRNA conjugates for tumor-targeted RNAi therapy
Jong Won Lee
, Jiwon Choi
,
Yeonho Choi
, Kwangmeyung Kim
, Yoosoo Yang
, Sun Hwa Kim
, Hong Yeol Yoon
*
, Ick Chan Kwon
*
Corresponding author for this work
Research output
:
Contribution to journal
›
Article
›
peer-review
45
Citations (Scopus)
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Keyphrases
Tumor Targeting
100%
Small Interfering RNA (siRNA)
100%
RNA Interference Therapy
100%
RNA Therapeutics
37%
Delivery Strategy
25%
RNA Interference
25%
Delivery Efficiency
25%
Clinical Translation
25%
Liver
12%
Gene Regulation
12%
Pharmacokinetics
12%
Biocompatibility
12%
Cationic Polymer
12%
Cationic Lipids
12%
Strategies to Overcome
12%
Cellular Mechanisms
12%
Gene Activity
12%
Chemically Modified
12%
Double-stranded RNA
12%
Sequence Specificity
12%
Severe Toxicity
12%
RNA Molecules
12%
Small Interfering RNA (siRNA) Delivery
12%
Tumor-targeted Delivery
12%
Tumor-targeted Therapy
12%
Effective Treatment
12%
RNA Interference Technology
12%
RNA Degradation
12%
Carrier-free
12%
Bioconjugation
12%
Liver Targeting
12%
Peptide Polymers
12%
Therapeutic Platform
12%
Liver Accumulation
12%
Nonspecific Protein Adsorption
12%
Anti-peptide Antibody
12%
Cationic Nanocarriers
12%
Peptide Aptamer
12%
Lipid-polymer
12%
Pharmacology, Toxicology and Pharmaceutical Science
Neoplasm
100%
Small Interfering RNA
100%
Malignant Neoplasm
11%
Disease
11%
Nanocarrier
11%
Protein
11%
Double Stranded RNA
11%
Aptamer
11%
Bioconjugation
11%
Peptide Antibody
11%
Messenger RNA
11%
Pharmacokinetics
11%