Monitoring of Dose Distribution in Photon Therapy with Multiple-Scattering Compton Camera: A Monte Carlo Simulation Study

Taewoong Lee, Hyounggun Lee, Wonho Lee

Research output: Contribution to journalArticlepeer-review


This study evaluated the performance of a multiple-scattering Compton camera (MSCC) for in vivo monitoring of the dose distribution of therapeutic photons in various phantoms. When 6-MV photons interacted with materials in the phantom, most photons deposited part of their energies on the voxels and were scattered out of the phantom. The 3D distribution of the scattered photons detected by the MSCC was reconstructed by using image processing methods based on Compton kinematics. The optimized design parameters from previous studies were used in the current system. In order to verify the accuracy of dose estimation by using MSCC, the results of depth-dose distribution curves in the phantom were compared with theoretical values calculated by MCNPX for various phantoms. The dose distribution of scattered photons showed similar trends to the deposited dose of incident photons in various phantoms. For realistic visualization, the reconstructed Compton images were combined with Computed Tomography (CT) images of the phantom. The results of this study demonstrated the feasibility of using Compton imaging as a means of monitoring the 3D dose distribution of the therapeutic photons in radiation therapy. The combination of Compton and CT images of the human phantom highlighted the effectiveness of our MSCC for monitoring patient doses in 3D photon therapy.

Original languageEnglish
Article number7590063
Pages (from-to)2801-2806
Number of pages6
JournalIEEE Transactions on Nuclear Science
Issue number6
Publication statusPublished - 2016 Dec

Bibliographical note

Publisher Copyright:
© 2016 IEEE.


  • 3D dose distribution
  • Voxel phantom
  • multiple-scattering Compton camera

ASJC Scopus subject areas

  • Nuclear and High Energy Physics
  • Nuclear Energy and Engineering
  • Electrical and Electronic Engineering


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