Multi-component nanorods for vaccination applications

A. K. Salem; C. F. Hung; T. W. Kim; T. C. Wu; P. C. Searson; K. W. Leong

doi:10.1088/0957-4484/16/4/025

Multi-component nanorods for vaccination applications

A. K. Salem, C. F. Hung, T. W. Kim, T. C. Wu, P. C. Searson, K. W. Leong

Research output: Contribution to journal › Article › peer-review

34 Citations (Scopus)

Abstract

Immune responses from Au/Ni nanorods prepared by electrochemical deposition in alumina templates are evaluated in C57BL/6 mice. When the nanorods are bombarded into skin, they generate a strong CDS T-cell and antibody response. When pcDNA3 is bound to the Ni segment of the nanorod, it provides a strong immunostimulatory adjuvant effect to the antigen bound on the Au segment.

Original language	English
Pages (from-to)	484-487
Number of pages	4
Journal	Nanotechnology
Volume	16
Issue number	4
DOIs	https://doi.org/10.1088/0957-4484/16/4/025
Publication status	Published - 2005 Apr
Externally published	Yes

ASJC Scopus subject areas

Bioengineering
Chemistry(all)
Materials Science(all)
Mechanics of Materials
Mechanical Engineering
Electrical and Electronic Engineering

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1088/0957-4484/16/4/025

Cite this

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author = "Salem, {A. K.} and Hung, {C. F.} and Kim, {T. W.} and Wu, {T. C.} and Searson, {P. C.} and Leong, {K. W.}",

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AU - Salem, A. K.

AU - Hung, C. F.

AU - Kim, T. W.

AU - Wu, T. C.

AU - Searson, P. C.

AU - Leong, K. W.

PY - 2005/4

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AB - Immune responses from Au/Ni nanorods prepared by electrochemical deposition in alumina templates are evaluated in C57BL/6 mice. When the nanorods are bombarded into skin, they generate a strong CDS T-cell and antibody response. When pcDNA3 is bound to the Ni segment of the nanorod, it provides a strong immunostimulatory adjuvant effect to the antigen bound on the Au segment.

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Multi-component nanorods for vaccination applications

Abstract

ASJC Scopus subject areas

UN SDGs

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