Multiple Granulation Tissues during Acitretin Therapy

Sang Hyuk Woo, Ho Sup Lee, Hwa Jung Ryu, Dong Soo Yu, Hae Jun Song, Chil Hwan Oh

    Research output: Contribution to journalArticlepeer-review


    Acitretin, the principal and free acid metabolite of etretinate, is used to treat patients with several types of psoriasis. The common side effects encountered with acitretin therapy are cheilitis, conjunctivitis, xerosis, dryness of the nasal mucosa with minor nosebleeds, pruritis, and desquamation of the palms and soles. Granulation tissue is a well recognized side effect of oral acitretin. This reaction is characterized by ulceration, hemorrhagic crusting and excess granulation tissue. It occurs between the third and 12th weeks of therapy, most commonly affects the hands and feet. We present a case of multiple granulation tissues associated with acitretin therapy.

    Original languageEnglish
    Pages (from-to)95-97
    Number of pages3
    JournalKorean Journal of Dermatology
    Issue number1
    Publication statusPublished - 2004 Jan


    • Acitretin
    • Granulation tissue
    • Retinoid

    ASJC Scopus subject areas

    • Dermatology


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