Nano web based novel microchip for artificial kidney

Kwang Ho Lee, Duck Joong Kim, Byoung Goo Min, Sang Hoon Lee

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    2 Citations (Scopus)

    Abstract

    In this study, a novel artificial renal replacement system is presented using a biocompatible polymeric nanofibers and MEMS technology. Usually, a classical artificial renal replacement system employs a semi-permeable membrane based hemodialyzer that replaces an ability of the kidney by removing metabolic toxins through diffusion and hydraulic pressure gradients. But, it has some limits in efficient filtration of metabolic byproducts (e.g.: urea, creatinine, and so on). We have developed PDMS based artificial renal microchips integrating biocompatible polymeric nanofibers which are utilized for the filtration of blood. Here, we demonstrate a new artificial renal chip by integrating a high efficient biocompatible polymeric nanofibers membrane with the PDMS based micro - fluidic platform. Via the optimization of PDMS micro fluidic channel network and the multiple packaging of nanofibers membrane, we will realize the portable and wearable artificial kidney system.

    Original languageEnglish
    Title of host publicationIFMBE Proceedings
    EditorsSun I. Kim, Tae Suk Suh
    PublisherSpringer Verlag
    Pages279-282
    Number of pages4
    Edition1
    ISBN (Print)9783540368397
    DOIs
    Publication statusPublished - 2007
    Event10th World Congress on Medical Physics and Biomedical Engineering, WC 2006 - Seoul, Korea, Republic of
    Duration: 2006 Aug 272006 Sept 1

    Publication series

    NameIFMBE Proceedings
    Number1
    Volume14
    ISSN (Print)1680-0737
    ISSN (Electronic)1433-9277

    Other

    Other10th World Congress on Medical Physics and Biomedical Engineering, WC 2006
    Country/TerritoryKorea, Republic of
    CitySeoul
    Period06/8/2706/9/1

    Bibliographical note

    Publisher Copyright:
    © International Federation for Medical and Biological Engineering 2007.

    Keywords

    • Artificial kidney
    • Nanofiber
    • PDMS
    • Renal chip

    ASJC Scopus subject areas

    • Bioengineering
    • Biomedical Engineering

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