Nano web based novel microchip for artificial kidney

Kwang Ho Lee; Duck Joong Kim; Byoung Goo Min; Sang Hoon Lee

doi:10.1007/978-3-540-36841-0_78

Nano web based novel microchip for artificial kidney

Kwang Ho Lee, Duck Joong Kim, Byoung Goo Min, Sang Hoon Lee

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

2 Citations (Scopus)

Abstract

In this study, a novel artificial renal replacement system is presented using a biocompatible polymeric nanofibers and MEMS technology. Usually, a classical artificial renal replacement system employs a semi-permeable membrane based hemodialyzer that replaces an ability of the kidney by removing metabolic toxins through diffusion and hydraulic pressure gradients. But, it has some limits in efficient filtration of metabolic byproducts (e.g.: urea, creatinine, and so on). We have developed PDMS based artificial renal microchips integrating biocompatible polymeric nanofibers which are utilized for the filtration of blood. Here, we demonstrate a new artificial renal chip by integrating a high efficient biocompatible polymeric nanofibers membrane with the PDMS based micro - fluidic platform. Via the optimization of PDMS micro fluidic channel network and the multiple packaging of nanofibers membrane, we will realize the portable and wearable artificial kidney system.

Original language	English
Title of host publication	IFMBE Proceedings
Editors	Sun I. Kim, Tae Suk Suh
Publisher	Springer Verlag
Pages	279-282
Number of pages	4
Edition	1
ISBN (Print)	9783540368397
DOIs	https://doi.org/10.1007/978-3-540-36841-0_78
Publication status	Published - 2007
Event	10th World Congress on Medical Physics and Biomedical Engineering, WC 2006 - Seoul, Korea, Republic of Duration: 2006 Aug 27 → 2006 Sept 1

Publication series

Name	IFMBE Proceedings
Number	1
Volume	14
ISSN (Print)	1680-0737
ISSN (Electronic)	1433-9277

Other

Other	10th World Congress on Medical Physics and Biomedical Engineering, WC 2006
Country/Territory	Korea, Republic of
City	Seoul
Period	06/8/27 → 06/9/1

Bibliographical note

Publisher Copyright:
© International Federation for Medical and Biological Engineering 2007.

Keywords

Artificial kidney
Nanofiber
PDMS
Renal chip

ASJC Scopus subject areas

Bioengineering
Biomedical Engineering

Access to Document

10.1007/978-3-540-36841-0_78

Cite this

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title = "Nano web based novel microchip for artificial kidney",

abstract = "In this study, a novel artificial renal replacement system is presented using a biocompatible polymeric nanofibers and MEMS technology. Usually, a classical artificial renal replacement system employs a semi-permeable membrane based hemodialyzer that replaces an ability of the kidney by removing metabolic toxins through diffusion and hydraulic pressure gradients. But, it has some limits in efficient filtration of metabolic byproducts (e.g.: urea, creatinine, and so on). We have developed PDMS based artificial renal microchips integrating biocompatible polymeric nanofibers which are utilized for the filtration of blood. Here, we demonstrate a new artificial renal chip by integrating a high efficient biocompatible polymeric nanofibers membrane with the PDMS based micro - fluidic platform. Via the optimization of PDMS micro fluidic channel network and the multiple packaging of nanofibers membrane, we will realize the portable and wearable artificial kidney system.",

keywords = "Artificial kidney, Nanofiber, PDMS, Renal chip",

author = "Lee, {Kwang Ho} and Kim, {Duck Joong} and Min, {Byoung Goo} and Lee, {Sang Hoon}",

note = "Publisher Copyright: {\textcopyright} International Federation for Medical and Biological Engineering 2007.; 10th World Congress on Medical Physics and Biomedical Engineering, WC 2006 ; Conference date: 27-08-2006 Through 01-09-2006",

year = "2007",

doi = "10.1007/978-3-540-36841-0_78",

language = "English",

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AU - Lee, Kwang Ho

AU - Kim, Duck Joong

AU - Min, Byoung Goo

AU - Lee, Sang Hoon

N1 - Publisher Copyright: © International Federation for Medical and Biological Engineering 2007.

PY - 2007

Y1 - 2007

N2 - In this study, a novel artificial renal replacement system is presented using a biocompatible polymeric nanofibers and MEMS technology. Usually, a classical artificial renal replacement system employs a semi-permeable membrane based hemodialyzer that replaces an ability of the kidney by removing metabolic toxins through diffusion and hydraulic pressure gradients. But, it has some limits in efficient filtration of metabolic byproducts (e.g.: urea, creatinine, and so on). We have developed PDMS based artificial renal microchips integrating biocompatible polymeric nanofibers which are utilized for the filtration of blood. Here, we demonstrate a new artificial renal chip by integrating a high efficient biocompatible polymeric nanofibers membrane with the PDMS based micro - fluidic platform. Via the optimization of PDMS micro fluidic channel network and the multiple packaging of nanofibers membrane, we will realize the portable and wearable artificial kidney system.

AB - In this study, a novel artificial renal replacement system is presented using a biocompatible polymeric nanofibers and MEMS technology. Usually, a classical artificial renal replacement system employs a semi-permeable membrane based hemodialyzer that replaces an ability of the kidney by removing metabolic toxins through diffusion and hydraulic pressure gradients. But, it has some limits in efficient filtration of metabolic byproducts (e.g.: urea, creatinine, and so on). We have developed PDMS based artificial renal microchips integrating biocompatible polymeric nanofibers which are utilized for the filtration of blood. Here, we demonstrate a new artificial renal chip by integrating a high efficient biocompatible polymeric nanofibers membrane with the PDMS based micro - fluidic platform. Via the optimization of PDMS micro fluidic channel network and the multiple packaging of nanofibers membrane, we will realize the portable and wearable artificial kidney system.

KW - Artificial kidney

KW - Nanofiber

KW - PDMS

KW - Renal chip

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BT - IFMBE Proceedings

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PB - Springer Verlag

T2 - 10th World Congress on Medical Physics and Biomedical Engineering, WC 2006

Y2 - 27 August 2006 through 1 September 2006

ER -

Nano web based novel microchip for artificial kidney

Abstract

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Bibliographical note

Keywords

ASJC Scopus subject areas

Access to Document

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