Nanobubbles from gas-generating polymeric nanoparticles: Ultrasound imaging of living subjects

Eunah Kang; Hyun Su Min; Jaeyoung Lee; Moon Hee Han; Hyung Jun Ahn; In Chan Yoon; Kuiwon Choi; Kwangmeyoung Kim; Kinam Park; Ick Chan Kwon

doi:10.1002/anie.200903841

Nanobubbles from gas-generating polymeric nanoparticles: Ultrasound imaging of living subjects

Eunah Kang^*, Hyun Su Min, Jaeyoung Lee, Moon Hee Han, Hyung Jun Ahn, In Chan Yoon, Kuiwon Choi, Kwangmeyoung Kim, Kinam Park, Ick Chan Kwon

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

109 Citations (Scopus)

Abstract

(Figure Presented) A bubbly personality: Coalescence and fusion of carbon dioxide nanobubbles in a tumor leads to microbubbles that can be imaged by ultrasound (see picture). The bubbles are released from gas-generating polymeric nanoparticles that are coated with hydrophobically modified chitosan. Hydrolysis of the polymer poly(BL-PO), which consists of a biodegradable main backbone and a carbonate side chain, results in the release of carbon dioxide.

Original language	English
Pages (from-to)	524-528
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	49
Issue number	3
DOIs	https://doi.org/10.1002/anie.200903841
Publication status	Published - 2010 Jan 12

Keywords

Carbon dioxide
Imaging agents
Nanostructures
Polymers
Ultrasound

ASJC Scopus subject areas

Catalysis
General Chemistry

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10.1002/anie.200903841

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abstract = "(Figure Presented) A bubbly personality: Coalescence and fusion of carbon dioxide nanobubbles in a tumor leads to microbubbles that can be imaged by ultrasound (see picture). The bubbles are released from gas-generating polymeric nanoparticles that are coated with hydrophobically modified chitosan. Hydrolysis of the polymer poly(BL-PO), which consists of a biodegradable main backbone and a carbonate side chain, results in the release of carbon dioxide.",

keywords = "Carbon dioxide, Imaging agents, Nanostructures, Polymers, Ultrasound",

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T2 - Ultrasound imaging of living subjects

AU - Kang, Eunah

AU - Min, Hyun Su

AU - Lee, Jaeyoung

AU - Han, Moon Hee

AU - Ahn, Hyung Jun

AU - Yoon, In Chan

AU - Choi, Kuiwon

AU - Kim, Kwangmeyoung

AU - Park, Kinam

AU - Kwon, Ick Chan

PY - 2010/1/12

Y1 - 2010/1/12

N2 - (Figure Presented) A bubbly personality: Coalescence and fusion of carbon dioxide nanobubbles in a tumor leads to microbubbles that can be imaged by ultrasound (see picture). The bubbles are released from gas-generating polymeric nanoparticles that are coated with hydrophobically modified chitosan. Hydrolysis of the polymer poly(BL-PO), which consists of a biodegradable main backbone and a carbonate side chain, results in the release of carbon dioxide.

AB - (Figure Presented) A bubbly personality: Coalescence and fusion of carbon dioxide nanobubbles in a tumor leads to microbubbles that can be imaged by ultrasound (see picture). The bubbles are released from gas-generating polymeric nanoparticles that are coated with hydrophobically modified chitosan. Hydrolysis of the polymer poly(BL-PO), which consists of a biodegradable main backbone and a carbonate side chain, results in the release of carbon dioxide.

KW - Carbon dioxide

KW - Imaging agents

KW - Nanostructures

KW - Polymers

KW - Ultrasound

UR - https://www.scopus.com/pages/publications/74549145150

U2 - 10.1002/anie.200903841

DO - 10.1002/anie.200903841

M3 - Article

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AN - SCOPUS:74549145150

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VL - 49

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JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 3

ER -

Nanobubbles from gas-generating polymeric nanoparticles: Ultrasound imaging of living subjects

Abstract

Keywords

ASJC Scopus subject areas

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