Abstract
Integrated biomimetic systems with nanofiber polymer networks and microfluidic chips were fabricated and cellular behaviors were observed by changing surface characteristics of nanofiber matrices and flow rates of microchannels. Human MSCs were seeded on the nanofiber matrices and a morphological investigation with actin filament staining and SEM was performed. Integration of nanofiber matrices into the microchannels provides the useful tools for mimicking cellular microenvironments and elucidating basic questions of cell and ECM assembly and interactions.
| Original language | English |
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| Pages | 1190-1192 |
| Number of pages | 3 |
| Publication status | Published - 2008 |
| Event | 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States Duration: 2008 Oct 12 → 2008 Oct 16 |
Other
| Other | 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 |
|---|---|
| Country/Territory | United States |
| City | San Diego, CA |
| Period | 08/10/12 → 08/10/16 |
Keywords
- Biomimetic system
- Cell culture chip
- Human mesenchymal stem cell
- Nanofiber
ASJC Scopus subject areas
- Chemical Engineering (miscellaneous)
- Bioengineering