Nanofiber matrix based microchip for human mesenchymal stem cell culture

K. H. Lee, S. J. Shin, Y. Park, D. K. Han, J. J. Park, S. H. Lee

Research output: Contribution to conferencePaperpeer-review

Abstract

Integrated biomimetic systems with nanofiber polymer networks and microfluidic chips were fabricated and cellular behaviors were observed by changing surface characteristics of nanofiber matrices and flow rates of microchannels. Human MSCs were seeded on the nanofiber matrices and a morphological investigation with actin filament staining and SEM was performed. Integration of nanofiber matrices into the microchannels provides the useful tools for mimicking cellular microenvironments and elucidating basic questions of cell and ECM assembly and interactions.

Original languageEnglish
Pages1190-1192
Number of pages3
Publication statusPublished - 2008
Event12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States
Duration: 2008 Oct 122008 Oct 16

Other

Other12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008
Country/TerritoryUnited States
CitySan Diego, CA
Period08/10/1208/10/16

Keywords

  • Biomimetic system
  • Cell culture chip
  • Human mesenchymal stem cell
  • Nanofiber

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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