Nanofiber matrix based microchip for human mesenchymal stem cell culture

K. H. Lee, S. J. Shin, Y. Park, D. K. Han, J. J. Park, S. H. Lee

    Research output: Contribution to conferencePaperpeer-review

    Abstract

    Integrated biomimetic systems with nanofiber polymer networks and microfluidic chips were fabricated and cellular behaviors were observed by changing surface characteristics of nanofiber matrices and flow rates of microchannels. Human MSCs were seeded on the nanofiber matrices and a morphological investigation with actin filament staining and SEM was performed. Integration of nanofiber matrices into the microchannels provides the useful tools for mimicking cellular microenvironments and elucidating basic questions of cell and ECM assembly and interactions.

    Original languageEnglish
    Pages1190-1192
    Number of pages3
    Publication statusPublished - 2008
    Event12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States
    Duration: 2008 Oct 122008 Oct 16

    Other

    Other12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008
    Country/TerritoryUnited States
    CitySan Diego, CA
    Period08/10/1208/10/16

    Keywords

    • Biomimetic system
    • Cell culture chip
    • Human mesenchymal stem cell
    • Nanofiber

    ASJC Scopus subject areas

    • Chemical Engineering (miscellaneous)
    • Bioengineering

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