Nanofiber matrix based microchip for human mesenchymal stem cell culture

K. H. Lee; S. J. Shin; Y. Park; D. K. Han; J. J. Park; S. H. Lee

Nanofiber matrix based microchip for human mesenchymal stem cell culture

K. H. Lee, S. J. Shin, Y. Park, D. K. Han, J. J. Park, S. H. Lee

Research output: Contribution to conference › Paper › peer-review

Abstract

Integrated biomimetic systems with nanofiber polymer networks and microfluidic chips were fabricated and cellular behaviors were observed by changing surface characteristics of nanofiber matrices and flow rates of microchannels. Human MSCs were seeded on the nanofiber matrices and a morphological investigation with actin filament staining and SEM was performed. Integration of nanofiber matrices into the microchannels provides the useful tools for mimicking cellular microenvironments and elucidating basic questions of cell and ECM assembly and interactions.

Original language	English
Pages	1190-1192
Number of pages	3
Publication status	Published - 2008
Event	12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States Duration: 2008 Oct 12 → 2008 Oct 16

Other

Other	12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008
Country/Territory	United States
City	San Diego, CA
Period	08/10/12 → 08/10/16

Keywords

Biomimetic system
Cell culture chip
Human mesenchymal stem cell
Nanofiber

ASJC Scopus subject areas

Chemical Engineering (miscellaneous)
Bioengineering

Cite this

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title = "Nanofiber matrix based microchip for human mesenchymal stem cell culture",

abstract = "Integrated biomimetic systems with nanofiber polymer networks and microfluidic chips were fabricated and cellular behaviors were observed by changing surface characteristics of nanofiber matrices and flow rates of microchannels. Human MSCs were seeded on the nanofiber matrices and a morphological investigation with actin filament staining and SEM was performed. Integration of nanofiber matrices into the microchannels provides the useful tools for mimicking cellular microenvironments and elucidating basic questions of cell and ECM assembly and interactions.",

keywords = "Biomimetic system, Cell culture chip, Human mesenchymal stem cell, Nanofiber",

author = "Lee, {K. H.} and Shin, {S. J.} and Y. Park and Han, {D. K.} and Park, {J. J.} and Lee, {S. H.}",

year = "2008",

language = "English",

pages = "1190--1192",

note = "12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 ; Conference date: 12-10-2008 Through 16-10-2008",

}

TY - CONF

T1 - Nanofiber matrix based microchip for human mesenchymal stem cell culture

AU - Lee, K. H.

AU - Shin, S. J.

AU - Park, Y.

AU - Han, D. K.

AU - Park, J. J.

AU - Lee, S. H.

PY - 2008

Y1 - 2008

N2 - Integrated biomimetic systems with nanofiber polymer networks and microfluidic chips were fabricated and cellular behaviors were observed by changing surface characteristics of nanofiber matrices and flow rates of microchannels. Human MSCs were seeded on the nanofiber matrices and a morphological investigation with actin filament staining and SEM was performed. Integration of nanofiber matrices into the microchannels provides the useful tools for mimicking cellular microenvironments and elucidating basic questions of cell and ECM assembly and interactions.

AB - Integrated biomimetic systems with nanofiber polymer networks and microfluidic chips were fabricated and cellular behaviors were observed by changing surface characteristics of nanofiber matrices and flow rates of microchannels. Human MSCs were seeded on the nanofiber matrices and a morphological investigation with actin filament staining and SEM was performed. Integration of nanofiber matrices into the microchannels provides the useful tools for mimicking cellular microenvironments and elucidating basic questions of cell and ECM assembly and interactions.

KW - Biomimetic system

KW - Cell culture chip

KW - Human mesenchymal stem cell

KW - Nanofiber

UR - http://www.scopus.com/inward/record.url?scp=84902470215&partnerID=8YFLogxK

M3 - Paper

AN - SCOPUS:84902470215

SP - 1190

EP - 1192

T2 - 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008

Y2 - 12 October 2008 through 16 October 2008

ER -

Nanofiber matrix based microchip for human mesenchymal stem cell culture

Abstract

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Keywords

ASJC Scopus subject areas

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