Nanomechanical microcantilever for In-Vitro biomolecular detection

Kilho Eom; Tae Yun Kwon; Jinsung Park; Sungsoo Na; Dae Sung Yoon; Tae Song Kim

doi:10.1115/IMECE2007-41290

Nanomechanical microcantilever for In-Vitro biomolecular detection

Kilho Eom, Tae Yun Kwon, Jinsung Park, Sungsoo Na, Dae Sung Yoon, Tae Song Kim

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Nanomechanical microcantilevers have enabled the sensitive label-free detection of chemical and/or biological molecules. In recent years, resonating microcantilevers have achieved the unprecedented sensitivity in detecting molecules. In this article, we review our current works on the label-free detection of biomolecules based on resonating microcantilevers. Our piezoelectric thick film microcantilevers exhibit the relatively high quality factor in a viscous liquid, indicating the potential of our cantilever to in situ biosensor applications for real-time detection of biomolecular interactions. It is shown that our microcantilevers allow the noise-free real-time monitoring of biomolecular recognitions, providing the insight into kinetics of biomolecular recognitions.

Original language	English
Title of host publication	Proceedings of the ASME International Mechanical Engineering Congress and Exposition, IMECE 2007
Pages	821-842
Number of pages	22
DOIs	https://doi.org/10.1115/IMECE2007-41290
Publication status	Published - 2008
Event	ASME International Mechanical Engineering Congress and Exposition, IMECE 2007 - Seattle, WA, United States Duration: 2007 Nov 11 → 2007 Nov 15

Publication series

Name	ASME International Mechanical Engineering Congress and Exposition, Proceedings
Volume	10 PART B

Other

Other	ASME International Mechanical Engineering Congress and Exposition, IMECE 2007
Country/Territory	United States
City	Seattle, WA
Period	07/11/11 → 07/11/15

Keywords

Biomolecular recognition
Biosensor
In-situ real-time monitoring
Microcantilever
Resonator

ASJC Scopus subject areas

Engineering(all)
Mechanical Engineering

Access to Document

10.1115/IMECE2007-41290

Cite this

Eom, K., Kwon, T. Y., Park, J., Na, S., Yoon, D. S., & Kim, T. S. (2008). Nanomechanical microcantilever for In-Vitro biomolecular detection. In Proceedings of the ASME International Mechanical Engineering Congress and Exposition, IMECE 2007 (pp. 821-842). (ASME International Mechanical Engineering Congress and Exposition, Proceedings; Vol. 10 PART B). https://doi.org/10.1115/IMECE2007-41290

Nanomechanical microcantilever for In-Vitro biomolecular detection. / Eom, Kilho; Kwon, Tae Yun; Park, Jinsung et al.
Proceedings of the ASME International Mechanical Engineering Congress and Exposition, IMECE 2007. 2008. p. 821-842 (ASME International Mechanical Engineering Congress and Exposition, Proceedings; Vol. 10 PART B).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Eom, K, Kwon, TY, Park, J, Na, S , Yoon, DS & Kim, TS 2008, Nanomechanical microcantilever for In-Vitro biomolecular detection. in Proceedings of the ASME International Mechanical Engineering Congress and Exposition, IMECE 2007. ASME International Mechanical Engineering Congress and Exposition, Proceedings, vol. 10 PART B, pp. 821-842, ASME International Mechanical Engineering Congress and Exposition, IMECE 2007, Seattle, WA, United States, 07/11/11. https://doi.org/10.1115/IMECE2007-41290

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abstract = "Nanomechanical microcantilevers have enabled the sensitive label-free detection of chemical and/or biological molecules. In recent years, resonating microcantilevers have achieved the unprecedented sensitivity in detecting molecules. In this article, we review our current works on the label-free detection of biomolecules based on resonating microcantilevers. Our piezoelectric thick film microcantilevers exhibit the relatively high quality factor in a viscous liquid, indicating the potential of our cantilever to in situ biosensor applications for real-time detection of biomolecular interactions. It is shown that our microcantilevers allow the noise-free real-time monitoring of biomolecular recognitions, providing the insight into kinetics of biomolecular recognitions.",

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AU - Kim, Tae Song

PY - 2008

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N2 - Nanomechanical microcantilevers have enabled the sensitive label-free detection of chemical and/or biological molecules. In recent years, resonating microcantilevers have achieved the unprecedented sensitivity in detecting molecules. In this article, we review our current works on the label-free detection of biomolecules based on resonating microcantilevers. Our piezoelectric thick film microcantilevers exhibit the relatively high quality factor in a viscous liquid, indicating the potential of our cantilever to in situ biosensor applications for real-time detection of biomolecular interactions. It is shown that our microcantilevers allow the noise-free real-time monitoring of biomolecular recognitions, providing the insight into kinetics of biomolecular recognitions.

AB - Nanomechanical microcantilevers have enabled the sensitive label-free detection of chemical and/or biological molecules. In recent years, resonating microcantilevers have achieved the unprecedented sensitivity in detecting molecules. In this article, we review our current works on the label-free detection of biomolecules based on resonating microcantilevers. Our piezoelectric thick film microcantilevers exhibit the relatively high quality factor in a viscous liquid, indicating the potential of our cantilever to in situ biosensor applications for real-time detection of biomolecular interactions. It is shown that our microcantilevers allow the noise-free real-time monitoring of biomolecular recognitions, providing the insight into kinetics of biomolecular recognitions.

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Nanomechanical microcantilever for In-Vitro biomolecular detection

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