TY - GEN
T1 - Nanomechanical microcantilever for In-Vitro biomolecular detection
AU - Eom, Kilho
AU - Kwon, Tae Yun
AU - Park, Jinsung
AU - Na, Sungsoo
AU - Yoon, Dae Sung
AU - Kim, Tae Song
PY - 2008
Y1 - 2008
N2 - Nanomechanical microcantilevers have enabled the sensitive label-free detection of chemical and/or biological molecules. In recent years, resonating microcantilevers have achieved the unprecedented sensitivity in detecting molecules. In this article, we review our current works on the label-free detection of biomolecules based on resonating microcantilevers. Our piezoelectric thick film microcantilevers exhibit the relatively high quality factor in a viscous liquid, indicating the potential of our cantilever to in situ biosensor applications for real-time detection of biomolecular interactions. It is shown that our microcantilevers allow the noise-free real-time monitoring of biomolecular recognitions, providing the insight into kinetics of biomolecular recognitions.
AB - Nanomechanical microcantilevers have enabled the sensitive label-free detection of chemical and/or biological molecules. In recent years, resonating microcantilevers have achieved the unprecedented sensitivity in detecting molecules. In this article, we review our current works on the label-free detection of biomolecules based on resonating microcantilevers. Our piezoelectric thick film microcantilevers exhibit the relatively high quality factor in a viscous liquid, indicating the potential of our cantilever to in situ biosensor applications for real-time detection of biomolecular interactions. It is shown that our microcantilevers allow the noise-free real-time monitoring of biomolecular recognitions, providing the insight into kinetics of biomolecular recognitions.
KW - Biomolecular recognition
KW - Biosensor
KW - In-situ real-time monitoring
KW - Microcantilever
KW - Resonator
UR - http://www.scopus.com/inward/record.url?scp=44349108402&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=44349108402&partnerID=8YFLogxK
U2 - 10.1115/IMECE2007-41290
DO - 10.1115/IMECE2007-41290
M3 - Conference contribution
AN - SCOPUS:44349108402
SN - 0791843041
SN - 9780791843048
T3 - ASME International Mechanical Engineering Congress and Exposition, Proceedings
SP - 821
EP - 842
BT - Proceedings of the ASME International Mechanical Engineering Congress and Exposition, IMECE 2007
T2 - ASME International Mechanical Engineering Congress and Exposition, IMECE 2007
Y2 - 11 November 2007 through 15 November 2007
ER -