Nanomolar Hg(II) detection using nile blue chemodosimeter in biological media

Min Hee Lee, Soon W. Lee, Sang Hoon Kim, Chulhun Kang, Jong Seung Kim

Research output: Contribution to journalArticlepeer-review

228 Citations (Scopus)


A Nile blue-based chemodosimeter (1) was newly synthesized, and its application for detection of the Hg2+ ion in 100% aqueous solution was demonstrated. Upon its addition into aqueous Hg2+ ion solution, it exhibited a considerable blue-shift in its absorption and emission spectra, driven by a desulfurization reaction. Detection at an emission of 652 nm was extremely sensitive (less than 1.0 ppb), even in biological media such as blood plasma and albumin.

Original languageEnglish
Pages (from-to)2101-2104
Number of pages4
JournalOrganic Letters
Issue number10
Publication statusPublished - 2009 May 21

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry


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