Nanomolar Hg(II) detection using nile blue chemodosimeter in biological media

Min Hee Lee, Soon W. Lee, Sang Hoon Kim, Chulhun Kang, Jong Seung Kim

    Research output: Contribution to journalArticlepeer-review

    231 Citations (Scopus)

    Abstract

    A Nile blue-based chemodosimeter (1) was newly synthesized, and its application for detection of the Hg2+ ion in 100% aqueous solution was demonstrated. Upon its addition into aqueous Hg2+ ion solution, it exhibited a considerable blue-shift in its absorption and emission spectra, driven by a desulfurization reaction. Detection at an emission of 652 nm was extremely sensitive (less than 1.0 ppb), even in biological media such as blood plasma and albumin.

    Original languageEnglish
    Pages (from-to)2101-2104
    Number of pages4
    JournalOrganic Letters
    Volume11
    Issue number10
    DOIs
    Publication statusPublished - 2009 May 21

    ASJC Scopus subject areas

    • Biochemistry
    • Physical and Theoretical Chemistry
    • Organic Chemistry

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