Nanomolar Hg(II) detection using nile blue chemodosimeter in biological media

Min Hee Lee; Soon W. Lee; Sang Hoon Kim; Chulhun Kang; Jong Seung Kim

doi:10.1021/ol900542y

Nanomolar Hg(II) detection using nile blue chemodosimeter in biological media

Min Hee Lee, Soon W. Lee, Sang Hoon Kim, Chulhun Kang, Jong Seung Kim

Research output: Contribution to journal › Article › peer-review

230 Citations (Scopus)

Abstract

A Nile blue-based chemodosimeter (1) was newly synthesized, and its application for detection of the Hg²⁺ ion in 100% aqueous solution was demonstrated. Upon its addition into aqueous Hg²⁺ ion solution, it exhibited a considerable blue-shift in its absorption and emission spectra, driven by a desulfurization reaction. Detection at an emission of 652 nm was extremely sensitive (less than 1.0 ppb), even in biological media such as blood plasma and albumin.

Original language	English
Pages (from-to)	2101-2104
Number of pages	4
Journal	Organic Letters
Volume	11
Issue number	10
DOIs	https://doi.org/10.1021/ol900542y
Publication status	Published - 2009 May 21

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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title = "Nanomolar Hg(II) detection using nile blue chemodosimeter in biological media",

abstract = "A Nile blue-based chemodosimeter (1) was newly synthesized, and its application for detection of the Hg2+ ion in 100% aqueous solution was demonstrated. Upon its addition into aqueous Hg2+ ion solution, it exhibited a considerable blue-shift in its absorption and emission spectra, driven by a desulfurization reaction. Detection at an emission of 652 nm was extremely sensitive (less than 1.0 ppb), even in biological media such as blood plasma and albumin.",

author = "Lee, {Min Hee} and Lee, {Soon W.} and Kim, {Sang Hoon} and Chulhun Kang and Kim, {Jong Seung}",

year = "2009",

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AU - Lee, Min Hee

AU - Lee, Soon W.

AU - Kim, Sang Hoon

AU - Kang, Chulhun

AU - Kim, Jong Seung

PY - 2009/5/21

Y1 - 2009/5/21

N2 - A Nile blue-based chemodosimeter (1) was newly synthesized, and its application for detection of the Hg2+ ion in 100% aqueous solution was demonstrated. Upon its addition into aqueous Hg2+ ion solution, it exhibited a considerable blue-shift in its absorption and emission spectra, driven by a desulfurization reaction. Detection at an emission of 652 nm was extremely sensitive (less than 1.0 ppb), even in biological media such as blood plasma and albumin.

AB - A Nile blue-based chemodosimeter (1) was newly synthesized, and its application for detection of the Hg2+ ion in 100% aqueous solution was demonstrated. Upon its addition into aqueous Hg2+ ion solution, it exhibited a considerable blue-shift in its absorption and emission spectra, driven by a desulfurization reaction. Detection at an emission of 652 nm was extremely sensitive (less than 1.0 ppb), even in biological media such as blood plasma and albumin.

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U2 - 10.1021/ol900542y

DO - 10.1021/ol900542y

M3 - Article

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JO - Organic Letters

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ER -

Nanomolar Hg(II) detection using nile blue chemodosimeter in biological media

Abstract

ASJC Scopus subject areas

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