Peptide assemblies have received significant attention because of their important role in biology and applications in bionanotechnology. Despite recent efforts to elucidate the principles of peptide self-assembly for developing novel functional devices, peptide self-assembly on two-dimensional nanomaterials has remained challenging. Here, we report nature-inspired two-dimensional peptide self-assembly on pristine graphene via optimization of peptide-peptide and peptide-graphene interactions. Two-dimensional peptide self-assembly was designed based on statistical analyses of >104 protein structures existing in nature and atomistic simulation-based structure predictions. We characterized the structures and surface properties of the self-assembled peptide formed on pristine graphene. Our study provides insights into the formation of peptide assemblies coupled with two-dimensional nanomaterials for further development of nanobiocomposite devices.
Bibliographical noteFunding Information:
This work was supported by the National Research Foundation of Korea (NRF) under Grant No. NRF-2015R1A2A2A04002453, NRF-2017R1D1A1B03035855 and IBS-R015-D1 and the National Institute of Supercomputing and Network in Korea Institute of Science and Technology Information (KISTI) under Grant No. KSC-2017-C3-0002.
© 2017 American Chemical Society.
ASJC Scopus subject areas
- General Materials Science
- Physical and Theoretical Chemistry