Nature-Inspired Construction of Two-Dimensionally Self-Assembled Peptide on Pristine Graphene

Young Hyun No; Nam Hyeong Kim; Bramaramba Gnapareddy; Bumjoon Choi; Yong Tae Kim; Sreekantha Reddy Dugasani; One Sun Lee; Kook Han Kim; Young Seon Ko; Seungwoo Lee; Sang Woo Lee; Sung Ha Park; Kilho Eom; Yong Ho Kim

doi:10.1021/acs.jpclett.7b00996

Nature-Inspired Construction of Two-Dimensionally Self-Assembled Peptide on Pristine Graphene

Young Hyun No
, Nam Hyeong Kim
, Bramaramba Gnapareddy
, Bumjoon Choi
, Yong Tae Kim
, Sreekantha Reddy Dugasani
, One Sun Lee
, Kook Han Kim
, Young Seon Ko
, Seungwoo Lee
, Sang Woo Lee
, Sung Ha Park^*
, Kilho Eom
, Yong Ho Kim

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

Peptide assemblies have received significant attention because of their important role in biology and applications in bionanotechnology. Despite recent efforts to elucidate the principles of peptide self-assembly for developing novel functional devices, peptide self-assembly on two-dimensional nanomaterials has remained challenging. Here, we report nature-inspired two-dimensional peptide self-assembly on pristine graphene via optimization of peptide-peptide and peptide-graphene interactions. Two-dimensional peptide self-assembly was designed based on statistical analyses of >10⁴ protein structures existing in nature and atomistic simulation-based structure predictions. We characterized the structures and surface properties of the self-assembled peptide formed on pristine graphene. Our study provides insights into the formation of peptide assemblies coupled with two-dimensional nanomaterials for further development of nanobiocomposite devices.

Original language	English
Pages (from-to)	3734-3739
Number of pages	6
Journal	Journal of Physical Chemistry Letters
Volume	8
Issue number	16
DOIs	https://doi.org/10.1021/acs.jpclett.7b00996
Publication status	Published - 2017 Aug 17
Externally published	Yes

Bibliographical note

Funding Information:
This work was supported by the National Research Foundation of Korea (NRF) under Grant No. NRF-2015R1A2A2A04002453, NRF-2017R1D1A1B03035855 and IBS-R015-D1 and the National Institute of Supercomputing and Network in Korea Institute of Science and Technology Information (KISTI) under Grant No. KSC-2017-C3-0002.

Publisher Copyright:
© 2017 American Chemical Society.

ASJC Scopus subject areas

General Materials Science
Physical and Theoretical Chemistry

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Cite this

No, Y. H., Kim, N. H., Gnapareddy, B., Choi, B., Kim, Y. T., Dugasani, S. R., Lee, O. S., Kim, K. H., Ko, Y. S., Lee, S., Lee, S. W., Park, S. H., Eom, K., & Kim, Y. H. (2017). Nature-Inspired Construction of Two-Dimensionally Self-Assembled Peptide on Pristine Graphene. Journal of Physical Chemistry Letters, 8(16), 3734-3739. https://doi.org/10.1021/acs.jpclett.7b00996

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title = "Nature-Inspired Construction of Two-Dimensionally Self-Assembled Peptide on Pristine Graphene",

abstract = "Peptide assemblies have received significant attention because of their important role in biology and applications in bionanotechnology. Despite recent efforts to elucidate the principles of peptide self-assembly for developing novel functional devices, peptide self-assembly on two-dimensional nanomaterials has remained challenging. Here, we report nature-inspired two-dimensional peptide self-assembly on pristine graphene via optimization of peptide-peptide and peptide-graphene interactions. Two-dimensional peptide self-assembly was designed based on statistical analyses of >104 protein structures existing in nature and atomistic simulation-based structure predictions. We characterized the structures and surface properties of the self-assembled peptide formed on pristine graphene. Our study provides insights into the formation of peptide assemblies coupled with two-dimensional nanomaterials for further development of nanobiocomposite devices.",

author = "No, \{Young Hyun\} and Kim, \{Nam Hyeong\} and Bramaramba Gnapareddy and Bumjoon Choi and Kim, \{Yong Tae\} and Dugasani, \{Sreekantha Reddy\} and Lee, \{One Sun\} and Kim, \{Kook Han\} and Ko, \{Young Seon\} and Seungwoo Lee and Lee, \{Sang Woo\} and Park, \{Sung Ha\} and Kilho Eom and Kim, \{Yong Ho\}",

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AU - Kim, Yong Tae

AU - Dugasani, Sreekantha Reddy

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AU - Ko, Young Seon

AU - Lee, Seungwoo

AU - Lee, Sang Woo

AU - Park, Sung Ha

AU - Eom, Kilho

AU - Kim, Yong Ho

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Nature-Inspired Construction of Two-Dimensionally Self-Assembled Peptide on Pristine Graphene

Abstract

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