A biophotonic image sensor has been demonstrated by depositing a thin Au (gold) film on the single optical fiber by sputtering process to incorporate a self-contained reference plane, as well as to be sustainable for different contact interfacial medium. This side-viewing optical probe has been polished for 43°-49° angle in order to unilaterally reflect the beam to be focused with a micro dome-shape lens simply formed by high-energy melting process at the distal end of the standard single-mode fiber. The all fiber interferometric optics using a low (partial) coherence double-sided autocorrelator performing as a high-precision optical reflectometer at 1300 nm range noninvasively conducted a direct profiling of the depth information inside a biological tissue and for diagnosing brain tumors, as well as imaging subsurface depth profile for other turbid organic/inorganic samples. The optical probing imager, which normally operates in low power of 3 mW-7 mW has ∼ 35 dB signal-to-noise ratio (SNR) and a ∼ 15 μ m axial resolution (3-dB width of the reflected peak curve).
Bibliographical noteFunding Information:
Manuscript received October 29, 2010; accepted November 24, 2010. Date of publication December 06, 2010; date of current version February 01, 2012. This work was supported in part by the NIH grants BRP 1R01 EB 007969-01 and 1R21NS063131-01A1. This research was supported by the World Class University (WCU) program through the National Research Foundation of Korea funded by the Ministry of Education, Science and Technology (R31-10008). The associate editor coordinating the review of this paper and approving it for publication was Prof. Aime Lay-Ekuakille.
- Biomedical measurements
- biomedical transducers
- image sensors
- optical fiber devices
- optical reflectometry
ASJC Scopus subject areas
- Electrical and Electronic Engineering