New antifungal activity of penicillic acid against Phytophthora species

S. W. Kang, S. W. Kim

Research output: Contribution to journalArticlepeer-review

34 Citations (Scopus)


Penicillic acid was isolated from a culture filtrate of Aspergillus sclerotiorum. It had a high in vitro antifungal activity against Phytophthora spp., which has not been previously reported. MICs of penicillic acid were from 1 to 25 μg ml-1 against Phytophthora spp. Penicillic acid induced abnormal branch formation, apical branching, and swelling in P. capsici, in P. cactorum mycelia contained irregular branching and small spherical swelling at apices, in P. cambivora there was irregular branching and swelling, and in P. drechsleri there was irregular multiple spherical swelling at or near hyphal apices.

Original languageEnglish
Pages (from-to)695-698
Number of pages4
JournalBiotechnology letters
Issue number9
Publication statusPublished - 2004 May

Bibliographical note

Funding Information:
This study was supported by a Korea University Grant.


  • Aspergillus sclerotiorum
  • Morphological abnormality
  • Penicillic acid
  • Phytophthora species

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Applied Microbiology and Biotechnology


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