Abstract
Bioceramic and polymers have been used as matrices for bone tissue engineering, and successful bone regeneration depends on cellular interaction with these matrices. The aim of this study was to fabricate polymer/ceramics composites with a novel sintering method. Also, we prepared homogenous porous poly(lactide-co-glycolide (PLGA) scaffolds in the supercritical CO2. These scaffolds had homogenous porous structure and high tensile and compressive mechanical properties compared to the scaffold prepared by conventional solvent casting method. This study revealed that generating bioactive and porous polymer scaffolds with novel sintering method or supercritical fluid technique could be useful for bone tissue engineering.
Original language | English |
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Pages (from-to) | 261-270 |
Number of pages | 10 |
Journal | Journal of Cellular Plastics |
Volume | 47 |
Issue number | 3 |
DOIs | |
Publication status | Published - 2011 May |
Externally published | Yes |
Bibliographical note
Copyright:Copyright 2011 Elsevier B.V., All rights reserved.
Keywords
- composite scaffold
- novel sintering
- poly(lactide-co-glycolide)
- supercritical fluid
ASJC Scopus subject areas
- General Chemistry
- Polymers and Plastics
- Materials Chemistry