New non-quinone geldanamycin analogs from genetically engineered Streptomyces hygroscopicus

Cheng Zhu Wu; An Na Moon; Jae Hyuk Jang; Dongho Lee; Sun Young Kang; Joon Tae Park; Jong Seog Ahn; Bang Yeon Hwang; Young Ho Kim; Hong Sub Lee; Young Soo Hong

doi:10.1038/ja.2011.24

New non-quinone geldanamycin analogs from genetically engineered Streptomyces hygroscopicus

Cheng Zhu Wu, An Na Moon, Jae Hyuk Jang, Dongho Lee, Sun Young Kang, Joon Tae Park, Jong Seog Ahn, Bang Yeon Hwang, Young Ho Kim, Hong Sub Lee, Young Soo Hong

Research output: Contribution to journal › Comment/debate › peer-review

12 Citations (Scopus)

Original language	English
Pages (from-to)	461-463
Number of pages	3
Journal	Journal of Antibiotics
Volume	64
Issue number	6
DOIs	https://doi.org/10.1038/ja.2011.24
Publication status	Published - 2011 Jun

Bibliographical note

Funding Information:
This work was supported in part by the 21C Frontier Microbial Genomics and Application Center and Global R&D Center program, the Ministry of Science and Technology, Republic of Korea and by a grant from KRIBB Research Initiative Program. We thank the Korea Basic Science Institute for the NMR measurements

Keywords

Hsp90 inhibitor
biosynthetic engineering
geldanamycin
non-quinone geldanamycin

ASJC Scopus subject areas

Pharmacology
Drug Discovery

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10.1038/ja.2011.24

Cite this

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title = "New non-quinone geldanamycin analogs from genetically engineered Streptomyces hygroscopicus",

keywords = "Hsp90 inhibitor, biosynthetic engineering, geldanamycin, non-quinone geldanamycin",

author = "Wu, {Cheng Zhu} and Moon, {An Na} and Jang, {Jae Hyuk} and Dongho Lee and Kang, {Sun Young} and Park, {Joon Tae} and Ahn, {Jong Seog} and Hwang, {Bang Yeon} and Kim, {Young Ho} and Lee, {Hong Sub} and Hong, {Young Soo}",

note = "Funding Information: This work was supported in part by the 21C Frontier Microbial Genomics and Application Center and Global R&D Center program, the Ministry of Science and Technology, Republic of Korea and by a grant from KRIBB Research Initiative Program. We thank the Korea Basic Science Institute for the NMR measurements",

year = "2011",

month = jun,

doi = "10.1038/ja.2011.24",

language = "English",

volume = "64",

pages = "461--463",

journal = "Journal of Antibiotics",

issn = "0021-8820",

publisher = "Springer Nature",

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T1 - New non-quinone geldanamycin analogs from genetically engineered Streptomyces hygroscopicus

AU - Wu, Cheng Zhu

AU - Moon, An Na

AU - Jang, Jae Hyuk

AU - Lee, Dongho

AU - Kang, Sun Young

AU - Park, Joon Tae

AU - Ahn, Jong Seog

AU - Hwang, Bang Yeon

AU - Kim, Young Ho

AU - Lee, Hong Sub

AU - Hong, Young Soo

N1 - Funding Information: This work was supported in part by the 21C Frontier Microbial Genomics and Application Center and Global R&D Center program, the Ministry of Science and Technology, Republic of Korea and by a grant from KRIBB Research Initiative Program. We thank the Korea Basic Science Institute for the NMR measurements

PY - 2011/6

Y1 - 2011/6

KW - Hsp90 inhibitor

KW - biosynthetic engineering

KW - geldanamycin

KW - non-quinone geldanamycin

UR - http://www.scopus.com/inward/record.url?scp=79959736928&partnerID=8YFLogxK

U2 - 10.1038/ja.2011.24

DO - 10.1038/ja.2011.24

M3 - Comment/debate

C2 - 21448187

AN - SCOPUS:79959736928

SN - 0021-8820

VL - 64

SP - 461

EP - 463

JO - Journal of Antibiotics

JF - Journal of Antibiotics

IS - 6

ER -

New non-quinone geldanamycin analogs from genetically engineered Streptomyces hygroscopicus

Bibliographical note

Keywords

ASJC Scopus subject areas

Access to Document

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