New non-quinone geldanamycin analogs from genetically engineered Streptomyces hygroscopicus

Cheng Zhu Wu, An Na Moon, Jae Hyuk Jang, Dongho Lee, Sun Young Kang, Joon Tae Park, Jong Seog Ahn, Bang Yeon Hwang, Young Ho Kim, Hong Sub Lee, Young Soo Hong

Research output: Contribution to journalComment/debatepeer-review

12 Citations (Scopus)
Original languageEnglish
Pages (from-to)461-463
Number of pages3
JournalJournal of Antibiotics
Issue number6
Publication statusPublished - 2011 Jun

Bibliographical note

Funding Information:
This work was supported in part by the 21C Frontier Microbial Genomics and Application Center and Global R&D Center program, the Ministry of Science and Technology, Republic of Korea and by a grant from KRIBB Research Initiative Program. We thank the Korea Basic Science Institute for the NMR measurements


  • Hsp90 inhibitor
  • biosynthetic engineering
  • geldanamycin
  • non-quinone geldanamycin

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery

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