Non-local means resolution enhancement of lung 4D-CT data

Yu Zhang, Guorong Wu, Pew Thian Yap, Qianjin Feng, Jun Lian, Wufan Chen, Dinggang Shen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)


Image resolution in 4D-CT is a crucial bottleneck that needs to be overcome for improved dose planning in radiotherapy for lung cancer. In this paper, we propose a novel patch-based algorithm to enhance the image quality of 4D-CT data. Our premise is that anatomical information missing in one phase can be recovered from complementary information embedded in other phases. We employ a patch-based mechanism to propagate information across phases for reconstruction of intermediate slices in the axial direction, where resolution is normally the lowest. Specifically, structurally-matching and spatially-nearby patches are combined for reconstruction of each patch. For greater sensitivity to anatomical nuances, we further employ a quad-tree technique to adaptively partition each slice of the image in each phase for more fine-grained refinement. Our evaluation based on a public 4D-CT lung data indicates that our algorithm gives very promising results with significantly enhanced image structures.

Original languageEnglish
Title of host publicationMedical Image Computing and Computer-Assisted Intervention, MICCAI2012 - 15th International Conference, Proceedings
EditorsNicholas Ayache, Herve Delingette, Polina Golland, Kensaku Mori
PublisherSpringer Verlag
Number of pages9
ISBN (Print)9783642334146
Publication statusPublished - 2012
Event15th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2012 - Nice, France
Duration: 2012 Oct 12012 Oct 5

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume7510 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349


Conference15th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2012

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)


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