Norovirus in benign convulsions with mild gastroenteritis

Gun Ha Kim, Jung Hye Byeon, Deog Yong Lee, Hyun Ju Jeong, Baik Lin Eun

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)


Background: Benign convulsions with gastroenteritis (CwG) are defined as afebrile convulsions accompanying symptoms of gastroenteritis without evidence of laboratory derangement. Although the main pathogen has been known as rotavirus, since the introduction of rotavirus vaccine, associated viruses with CwG may have changed. Thus, we evaluated the viral association of CwG for patients admitting for recent 2.5 years. Methods: All patients hospitalized for CwG between November 2012 and May 2015 were included in our study. Stool specimens were tested with reverse transcription polymerase chain reaction for detecting norovirus and astrovirus and with enzyme immunoassay for rotavirus and enteric adenovirus. Clinical data was gathered via chart review. Results: Fifty patients were included. Except four patients who failed to collect stool samples, 46 patients were tested. Causative diarrheal viruses were detected in 38 patients and they were 29 norovirus, four rotavirus, four adenovirus, and one astrovirus. Norovirus was commonly identified during the months of November and December. No difference of the clinical characteristics and laboratory value was noted according to the number of seizure episodes. Conclusions: Norovirus is a common pathogen in CwG. Understanding the viral associations can facilitate recognition of CwG.

Original languageEnglish
Pages (from-to)1-5
Number of pages5
JournalItalian Journal of Pediatrics
Issue number1
Publication statusPublished - 2016 Nov 3
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2016 The Author(s).


  • Gastroenteritis
  • Norovirus
  • Pediatric
  • Seizures

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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