Novel calcium-binding GTPase (AtCBG) involved in ABA-mediated salt stress signaling in Arabidopsis

Kandakumar Jayasekaran; Kyung Nam Kim; Munusamy Vivekanandan; Jeong Sheop Shin; Sung Han Ok

doi:10.1007/s00299-006-0195-5

Novel calcium-binding GTPase (AtCBG) involved in ABA-mediated salt stress signaling in Arabidopsis

Kandakumar Jayasekaran, Kyung Nam Kim, Munusamy Vivekanandan, Jeong Sheop Shin, Sung Han Ok

Department of Life Sciences

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

We have identified a novel Ca²⁺-signal sensing GTPase (643 amino acid residues with an estimated molecular mass of 79 kDa) from the Arabidopsis genome database. This protein contains a RHO-like GTPase domain at the N-terminus (15-184 amino acids) and two calcium-binding EF-hand motifs (199-227 and 319-347 amino acids, respectively). It has the capability to bind calcium and hydrolyze GTP; in addition, its GTPase activity is regulated by changes in Ca²⁺ concentration. The expression of this gene was induced by ABA and salt stresses, and specific knock-out mutants were highly sensitive to ABA and salt treatments. These findings suggest that this protein is a novel ABA- and salt stress-related Ca²⁺ signal transducer.

Original language	English
Pages (from-to)	1255-1262
Number of pages	8
Journal	Plant Cell Reports
Volume	25
Issue number	11
DOIs	https://doi.org/10.1007/s00299-006-0195-5
Publication status	Published - 2006 Nov

Keywords

Abiotic stress
Ca
GTP-binding
Regulation of gene expression
Signal transduction

ASJC Scopus subject areas

Agronomy and Crop Science
Plant Science

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10.1007/s00299-006-0195-5

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title = "Novel calcium-binding GTPase (AtCBG) involved in ABA-mediated salt stress signaling in Arabidopsis",

abstract = "We have identified a novel Ca2+-signal sensing GTPase (643 amino acid residues with an estimated molecular mass of 79 kDa) from the Arabidopsis genome database. This protein contains a RHO-like GTPase domain at the N-terminus (15-184 amino acids) and two calcium-binding EF-hand motifs (199-227 and 319-347 amino acids, respectively). It has the capability to bind calcium and hydrolyze GTP; in addition, its GTPase activity is regulated by changes in Ca2+ concentration. The expression of this gene was induced by ABA and salt stresses, and specific knock-out mutants were highly sensitive to ABA and salt treatments. These findings suggest that this protein is a novel ABA- and salt stress-related Ca2+ signal transducer.",

keywords = "Abiotic stress, Ca, GTP-binding, Regulation of gene expression, Signal transduction",

author = "Kandakumar Jayasekaran and Kim, {Kyung Nam} and Munusamy Vivekanandan and Shin, {Jeong Sheop} and Ok, {Sung Han}",

note = "Funding Information: Acknowledgements This project was funded by a grant from the Special Grant Research Program funded by the Ministry of Agriculture and Forestry of the Korean Government, and also supported by grants from the Plant Signaling Network Research Center, Korea Science and Engineering Foundation. Copyright: Copyright 2008 Elsevier B.V., All rights reserved.",

year = "2006",

month = nov,

doi = "10.1007/s00299-006-0195-5",

language = "English",

volume = "25",

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journal = "Plant Cell Reports",

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AU - Jayasekaran, Kandakumar

AU - Kim, Kyung Nam

AU - Vivekanandan, Munusamy

AU - Shin, Jeong Sheop

AU - Ok, Sung Han

N1 - Funding Information: Acknowledgements This project was funded by a grant from the Special Grant Research Program funded by the Ministry of Agriculture and Forestry of the Korean Government, and also supported by grants from the Plant Signaling Network Research Center, Korea Science and Engineering Foundation. Copyright: Copyright 2008 Elsevier B.V., All rights reserved.

PY - 2006/11

Y1 - 2006/11

N2 - We have identified a novel Ca2+-signal sensing GTPase (643 amino acid residues with an estimated molecular mass of 79 kDa) from the Arabidopsis genome database. This protein contains a RHO-like GTPase domain at the N-terminus (15-184 amino acids) and two calcium-binding EF-hand motifs (199-227 and 319-347 amino acids, respectively). It has the capability to bind calcium and hydrolyze GTP; in addition, its GTPase activity is regulated by changes in Ca2+ concentration. The expression of this gene was induced by ABA and salt stresses, and specific knock-out mutants were highly sensitive to ABA and salt treatments. These findings suggest that this protein is a novel ABA- and salt stress-related Ca2+ signal transducer.

AB - We have identified a novel Ca2+-signal sensing GTPase (643 amino acid residues with an estimated molecular mass of 79 kDa) from the Arabidopsis genome database. This protein contains a RHO-like GTPase domain at the N-terminus (15-184 amino acids) and two calcium-binding EF-hand motifs (199-227 and 319-347 amino acids, respectively). It has the capability to bind calcium and hydrolyze GTP; in addition, its GTPase activity is regulated by changes in Ca2+ concentration. The expression of this gene was induced by ABA and salt stresses, and specific knock-out mutants were highly sensitive to ABA and salt treatments. These findings suggest that this protein is a novel ABA- and salt stress-related Ca2+ signal transducer.

KW - Abiotic stress

KW - Ca

KW - GTP-binding

KW - Regulation of gene expression

KW - Signal transduction

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SN - 0721-7714

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EP - 1262

JO - Plant Cell Reports

JF - Plant Cell Reports

IS - 11

ER -

Novel calcium-binding GTPase (AtCBG) involved in ABA-mediated salt stress signaling in Arabidopsis

Abstract

Keywords

ASJC Scopus subject areas

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