Abstract
We report a case of a 56-year-old woman with breast cancer, ovarian cancer, and diffuse large B-cell lymphoma with a BRCA1 gene mutation. Evidence is mounting that there is a large increase in the risk for hematologic malignancies among patients with genetic changes in the BRCA pathways. The genomic analysis demonstrated a frameshift mutation in the BRCA1 gene: 277_279delinsCC (Phe93fs). It is a novel BRCA1 mutation that has never been reported, and caused malignant lymphoma as well as breast and ovarian cancer.
| Original language | English |
|---|---|
| Pages (from-to) | 534-538 |
| Number of pages | 5 |
| Journal | Cancer Research and Treatment |
| Volume | 47 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2015 |
Bibliographical note
Publisher Copyright:© 2015 by the Korean Cancer Association.
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- BRCA1 gene
- Breast neoplasms
- Lymphoma
- Ovarian neoplasms
ASJC Scopus subject areas
- Oncology
- Cancer Research
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