Nuclear transport of STAT6 determines the matrix rigidity dependent M2 activation of macrophages

Keyphrases

• Activated Macrophages 20%
• Anti-inflammation 20%
• Extracellular Matrix 20%
• Extracellular Microenvironment 40%
• Filamentous Actin (F-actin) 40%
• Immune Response 40%
• Immunological Activation 20%
• Inflammatory Macrophages 20%
• Intranuclear 20%
• Long-term Adaptation 20%
• M1 Macrophages 20%
• M2 Activation 100%
• M2 Macrophages 40%
• Macrophage Activation 100%
• Macrophages 40%
• Matrix Rigidity 100%
• Mechanical Condition 20%
• Mechanical Cues 20%
• Mechanosensation 20%
• Mechanosensing 20%
• Mechanosensitive 40%
• Nuclear Transport 100%
• Phenotypic Heterogeneity 20%
• Physical Environment 20%
• Rigid Matrix 20%
• Signal Transducer and Activator of Transcription 6 100%
• Tissue Homeostasis 20%
• Tissue Repair 20%
• Transcription Factor 20%
• Wound Healing 20%
• Wound Tissue 20%

Immunology and Microbiology

• Actin 33%
• Homeostasis 16%
• Immune Response 33%
• M2 Macrophages 33%
• Macrophage 100%
• Nucleocytoplasmic Transport 100%
• Rigidity 100%
• STAT6 100%
• Tissue Repair 16%
• Transcription Factors 16%
• Wound Healing 16%
• Wound Tissue 16%

Biochemistry, Genetics and Molecular Biology

• Actin 25%
• Homeostasis 12%
• Immune Response 25%
• Macrophage 100%
• Mechanosensation 12%
• Nuclear Transport 100%
• Phenotypic Heterogeneity 12%
• Rigidity 100%
• STAT6 100%
• Tissue Repair 12%
• Transcription Factors 12%
• Wound Healing 12%