Nut consumption has favorable effects on lipid profiles of Korean women with metabolic syndrome

Young Joo Lee, Ga Eun Nam, Ji A. Seo, Taehyung Yoon, Ilwon Seo, Jin Hee Lee, Donggil Im, Kyeong Nyeo Bahn, Si An Jeong, Tae Seok Kang, Jae Hee Ahn, Do Hoon Kim, Nan Hee Kim

Research output: Contribution to journalArticlepeer-review

45 Citations (Scopus)


Nut consumption has been studied for its cardioprotective effects. However, the findings of clinical intervention studies are inconsistent; and no intervention studies have been conducted in the Korean population. We hypothesized that nut supplementation may have favorable influence on metabolic markers. Therefore, this study aimed to investigate the effects of nut consumption on metabolic parameters and biomarkers related to inflammation, oxidative stress, and endothelial function in Korean adults with metabolic syndrome. To this end, we designed a randomized, parallel, controlled dietary intervention study ( NCT02023749). Subjects with metabolic syndrome and a body mass index of at least 23 kg/m2 were randomized to the Control group and the Nut group, which received supplementation with 30 g/d of mixed nuts (walnuts, peanuts, and pine nuts) for 6 weeks. Sixty volunteers were included in the final analysis. Metabolic markers were evaluated at baseline and at the end of the study. Total cholesterol and non-high-density lipoprotein cholesterol levels significantly improved in the Nut group compared to those in the Control group (P =023 and P =016, respectively) in women. Biomarkers related to inflammation, oxidative stress, and endothelial function did not significantly change from baseline in either group. Thus, supplementing a usual diet with mixed nuts for 6 weeks had favorable effects on several lipid parameters in Korean women with metabolic syndrome. These findings present a possible mechanism for the cardioprotective effects of nut consumption.

Original languageEnglish
Pages (from-to)814-820
Number of pages7
JournalNutrition Research
Issue number9
Publication statusPublished - 2014 Sept 1
Externally publishedYes

Bibliographical note

Funding Information:
This research was supported by a grant ( 12161MFDS118 ) from the Ministry of Food and Drug Safety in 2012. The authors declare no conflicts of interest.

Publisher Copyright:
© 2014 Elsevier Inc.


  • Endothelial function
  • Inflammation
  • Lipid profile
  • Metabolic syndrome
  • Nuts
  • Oxidative stress

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology
  • Nutrition and Dietetics


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