TY - JOUR
T1 - Omnipotent phosphorene
T2 - a next-generation, two-dimensional nanoplatform for multidisciplinary biomedical applications
AU - Qiu, Meng
AU - Ren, Wen Xiu
AU - Jeong, Taeho
AU - Won, Miae
AU - Park, Geun Young
AU - Sang, David Kipkemoi
AU - Liu, Li Ping
AU - Zhang, Han
AU - Kim, Jong Seung
N1 - Publisher Copyright:
© The Royal Society of Chemistry.
PY - 2018/8/7
Y1 - 2018/8/7
N2 - Phosphorene, also known as single- or few-layer black phosphorus (FLBP), is a new member of the two-dimensional (2D) material family and has attracted significant attention in recent years for applications in optoelectronics, energy storage and biomedicine due to its unique physicochemical properties and excellent biocompatibility. FLBP is regarded as a potential biological imaging agent for cancer diagnosis due to its intrinsic fluorescence (FL) and photoacoustic (PA) properties and negligible cytotoxicity. FLBP-based photothermal and photodynamic therapies have emerged with excellent anti-tumour therapeutic efficacies due to their unique physical properties, such as near-infrared (NIR) optical absorbance, large extinction coefficients, biodegradability and reactive oxygen species (ROS) or heat generation upon light irradiation. Furthermore, FLBP is a promising drug delivery platform because of its high drug-loading capacity due to its puckered layer structure with an ultralarge surface area, and FLBP is size-controllable with facile surface chemical modification. Because of the marked advantages of FLBP nanomaterials in biomedical applications, an overview of the latest progress and paradigms of FLBP-based nanoplatforms for multidisciplinary biomedical applications is presented in this tutorial review.
AB - Phosphorene, also known as single- or few-layer black phosphorus (FLBP), is a new member of the two-dimensional (2D) material family and has attracted significant attention in recent years for applications in optoelectronics, energy storage and biomedicine due to its unique physicochemical properties and excellent biocompatibility. FLBP is regarded as a potential biological imaging agent for cancer diagnosis due to its intrinsic fluorescence (FL) and photoacoustic (PA) properties and negligible cytotoxicity. FLBP-based photothermal and photodynamic therapies have emerged with excellent anti-tumour therapeutic efficacies due to their unique physical properties, such as near-infrared (NIR) optical absorbance, large extinction coefficients, biodegradability and reactive oxygen species (ROS) or heat generation upon light irradiation. Furthermore, FLBP is a promising drug delivery platform because of its high drug-loading capacity due to its puckered layer structure with an ultralarge surface area, and FLBP is size-controllable with facile surface chemical modification. Because of the marked advantages of FLBP nanomaterials in biomedical applications, an overview of the latest progress and paradigms of FLBP-based nanoplatforms for multidisciplinary biomedical applications is presented in this tutorial review.
UR - http://www.scopus.com/inward/record.url?scp=85050905407&partnerID=8YFLogxK
U2 - 10.1039/c8cs00342d
DO - 10.1039/c8cs00342d
M3 - Review article
C2 - 29882569
AN - SCOPUS:85050905407
SN - 0306-0012
VL - 47
SP - 5588
EP - 5601
JO - Chemical Society Reviews
JF - Chemical Society Reviews
IS - 15
ER -