Ophthalmoplegia with skin necrosis after a hyaluronic acid filler injection

Beom Jun Kim, Hi Jin You, Ileok Jung, Deok Woo Kim

    Research output: Contribution to journalComment/debatepeer-review

    9 Citations (Scopus)


    Hyaluronic acid filler injection is commonly used for aesthetic purposes. However, many clinicians neglect the possibility of developing vascular occlusion and its devastating sequelae. Besides visual loss after iatrogenic ophthalmic artery occlusion, ophthalmoplegia without blindness is rare but may occur. Here, we report a 23-year-old woman with ptosis, lateral deviation of the right eye, and skin necrosis after hyaluronic acid filler injection. After hyaluronidase injection and steroid pulse therapy, ptosis and eye movement were completely restored. Skin necrosis was treated with a human epithelial growth factor ointment, followed by Nd:YAG laser. Complete healing with minimal scar was achieved.

    Original languageEnglish
    Pages (from-to)1307-1310
    Number of pages4
    JournalJournal of Cosmetic Dermatology
    Issue number6
    Publication statusPublished - 2020 Jun 1

    Bibliographical note

    Funding Information:
    This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea Ministry of Science and ICT (MSIT) (No. NRF‐2017R1C1B5077085).

    Publisher Copyright:
    © 2020 Wiley Periodicals, Inc.


    • hyaluronic acid filler
    • necrosis
    • oculomotor nerve palsy
    • ophthalmoplegia

    ASJC Scopus subject areas

    • Dermatology


    Dive into the research topics of 'Ophthalmoplegia with skin necrosis after a hyaluronic acid filler injection'. Together they form a unique fingerprint.

    Cite this