Optical resolution of DL-pipecolic acid by fermentation using Pseudomonas sp. PA09

Chan Soo Kim, Il Seok Lee, Namhyun Chung, Won Gi Bang

    Research output: Contribution to journalArticlepeer-review

    3 Citations (Scopus)

    Abstract

    Pseudomonas sp. PA09 was isolated from farm soil and used for the optical resolution of D-pipecolic acid from DL-pipecolic acid. The strain PA09 consumed L-pipecolic acid preferentially as the sole carbon and energy source, thus accumulating D-pipecolic acid in the culture broth. Optimization to improve the enantiomeric excess and yield was performed. The time course experiment showed that the strain PA09 consumed L-pipecolic acid almost to completion after 25 h of cultivation, and the enantiomeric excess and the yield (% of residual D-pipecolic acid) were 99.8 and 96.0%, respectively.

    Original languageEnglish
    Pages (from-to)217-221
    Number of pages5
    JournalJournal of microbiology and biotechnology
    Volume11
    Issue number2
    Publication statusPublished - 2001 Apr

    Keywords

    • D-pipecolic acid
    • Fermentation
    • Optical resolution
    • Pseudomonas sp.

    ASJC Scopus subject areas

    • Biotechnology
    • Applied Microbiology and Biotechnology

    Fingerprint

    Dive into the research topics of 'Optical resolution of DL-pipecolic acid by fermentation using Pseudomonas sp. PA09'. Together they form a unique fingerprint.

    Cite this