Optical resolution of RS-(±)-mandelic acid by pseudomonas sp

Byung Yong Kim; Ki Chul Hwang; Hee Sang Song; Namhyun Chung; Won Gi Bang

doi:10.1023/A:1005649908991

Optical resolution of RS-(±)-mandelic acid by pseudomonas sp

Byung Yong Kim, Ki Chul Hwang, Hee Sang Song, Namhyun Chung, Won Gi Bang

Department of Biosystems and Biotechnology

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

For the optical resolution of R-(-)-mandelic acid from (±)-mandelic acid, Pseudomonas sp. MA02, which assimilated S-(+)-mandelic acid as carbon and energy source, was isolated from soil. Using the fed-batch culture under optimal condition, R-(-)-mandelic acid was accumulated up to the maximum theoretical yield of 50% (30 g l^-1) and entiomeric excess of 99.4%.

Original language	English
Article number	312873
Pages (from-to)	1871-1875
Number of pages	5
Journal	Biotechnology letters
Volume	22
Issue number	23
DOIs	https://doi.org/10.1023/A:1005649908991
Publication status	Published - 2000

Bibliographical note

Funding Information:
This work is partially supported by an intramural research fund of Korea University, Seoul, Korea.

Keywords

Fed-batch fermentation
Mandelic acid
Optical resolution
Pseudomonas sp

ASJC Scopus subject areas

Biotechnology
Bioengineering
Applied Microbiology and Biotechnology

Access to Document

10.1023/A:1005649908991

Cite this

@article{c618a7e2104b4f109c4e267c170ba9b0,

title = "Optical resolution of RS-(±)-mandelic acid by pseudomonas sp",

abstract = "For the optical resolution of R-(-)-mandelic acid from (±)-mandelic acid, Pseudomonas sp. MA02, which assimilated S-(+)-mandelic acid as carbon and energy source, was isolated from soil. Using the fed-batch culture under optimal condition, R-(-)-mandelic acid was accumulated up to the maximum theoretical yield of 50% (30 g l-1) and entiomeric excess of 99.4%.",

keywords = "Fed-batch fermentation, Mandelic acid, Optical resolution, Pseudomonas sp",

author = "Kim, {Byung Yong} and Hwang, {Ki Chul} and Song, {Hee Sang} and Namhyun Chung and Bang, {Won Gi}",

note = "Funding Information: This work is partially supported by an intramural research fund of Korea University, Seoul, Korea.",

year = "2000",

doi = "10.1023/A:1005649908991",

language = "English",

volume = "22",

pages = "1871--1875",

journal = "Biotechnology letters",

issn = "0141-5492",

publisher = "Springer Netherlands",

number = "23",

}

TY - JOUR

T1 - Optical resolution of RS-(±)-mandelic acid by pseudomonas sp

AU - Kim, Byung Yong

AU - Hwang, Ki Chul

AU - Song, Hee Sang

AU - Chung, Namhyun

AU - Bang, Won Gi

N1 - Funding Information: This work is partially supported by an intramural research fund of Korea University, Seoul, Korea.

PY - 2000

Y1 - 2000

N2 - For the optical resolution of R-(-)-mandelic acid from (±)-mandelic acid, Pseudomonas sp. MA02, which assimilated S-(+)-mandelic acid as carbon and energy source, was isolated from soil. Using the fed-batch culture under optimal condition, R-(-)-mandelic acid was accumulated up to the maximum theoretical yield of 50% (30 g l-1) and entiomeric excess of 99.4%.

AB - For the optical resolution of R-(-)-mandelic acid from (±)-mandelic acid, Pseudomonas sp. MA02, which assimilated S-(+)-mandelic acid as carbon and energy source, was isolated from soil. Using the fed-batch culture under optimal condition, R-(-)-mandelic acid was accumulated up to the maximum theoretical yield of 50% (30 g l-1) and entiomeric excess of 99.4%.

KW - Fed-batch fermentation

KW - Mandelic acid

KW - Optical resolution

KW - Pseudomonas sp

UR - http://www.scopus.com/inward/record.url?scp=0034534910&partnerID=8YFLogxK

U2 - 10.1023/A:1005649908991

DO - 10.1023/A:1005649908991

M3 - Article

AN - SCOPUS:0034534910

SN - 0141-5492

VL - 22

SP - 1871

EP - 1875

JO - Biotechnology letters

JF - Biotechnology letters

IS - 23

M1 - 312873

ER -

Optical resolution of RS-(±)-mandelic acid by pseudomonas sp

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this