Optical resolution of RS-(±)-mandelic acid by pseudomonas sp

Byung Yong Kim, Ki Chul Hwang, Hee Sang Song, Namhyun Chung, Won Gi Bang

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)


For the optical resolution of R-(-)-mandelic acid from (±)-mandelic acid, Pseudomonas sp. MA02, which assimilated S-(+)-mandelic acid as carbon and energy source, was isolated from soil. Using the fed-batch culture under optimal condition, R-(-)-mandelic acid was accumulated up to the maximum theoretical yield of 50% (30 g l-1) and entiomeric excess of 99.4%.

Original languageEnglish
Article number312873
Pages (from-to)1871-1875
Number of pages5
JournalBiotechnology letters
Issue number23
Publication statusPublished - 2000

Bibliographical note

Funding Information:
This work is partially supported by an intramural research fund of Korea University, Seoul, Korea.


  • Fed-batch fermentation
  • Mandelic acid
  • Optical resolution
  • Pseudomonas sp

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Applied Microbiology and Biotechnology


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