Optical resolution of RS-(±)-mandelic acid by pseudomonas sp

Byung Yong Kim; Ki Chul Hwang; Hee Sang Song; Namhyun Chung; Won Gi Bang

doi:10.1023/A:1005649908991

Optical resolution of RS-(±)-mandelic acid by pseudomonas sp

Byung Yong Kim, Ki Chul Hwang, Hee Sang Song, Namhyun Chung, Won Gi Bang

Department of Biosystems and Biotechnology

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

For the optical resolution of R-(-)-mandelic acid from (±)-mandelic acid, Pseudomonas sp. MA02, which assimilated S-(+)-mandelic acid as carbon and energy source, was isolated from soil. Using the fed-batch culture under optimal condition, R-(-)-mandelic acid was accumulated up to the maximum theoretical yield of 50% (30 g l^-1) and entiomeric excess of 99.4%.

Original language	English
Article number	312873
Pages (from-to)	1871-1875
Number of pages	5
Journal	Biotechnology letters
Volume	22
Issue number	23
DOIs	https://doi.org/10.1023/A:1005649908991
Publication status	Published - 2000

Keywords

Fed-batch fermentation
Mandelic acid
Optical resolution
Pseudomonas sp

ASJC Scopus subject areas

Biotechnology
Bioengineering
Applied Microbiology and Biotechnology

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10.1023/A:1005649908991

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abstract = "For the optical resolution of R-(-)-mandelic acid from (±)-mandelic acid, Pseudomonas sp. MA02, which assimilated S-(+)-mandelic acid as carbon and energy source, was isolated from soil. Using the fed-batch culture under optimal condition, R-(-)-mandelic acid was accumulated up to the maximum theoretical yield of 50% (30 g l-1) and entiomeric excess of 99.4%.",

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T1 - Optical resolution of RS-(±)-mandelic acid by pseudomonas sp

AU - Kim, Byung Yong

AU - Hwang, Ki Chul

AU - Song, Hee Sang

AU - Chung, Namhyun

AU - Bang, Won Gi

PY - 2000

Y1 - 2000

N2 - For the optical resolution of R-(-)-mandelic acid from (±)-mandelic acid, Pseudomonas sp. MA02, which assimilated S-(+)-mandelic acid as carbon and energy source, was isolated from soil. Using the fed-batch culture under optimal condition, R-(-)-mandelic acid was accumulated up to the maximum theoretical yield of 50% (30 g l-1) and entiomeric excess of 99.4%.

AB - For the optical resolution of R-(-)-mandelic acid from (±)-mandelic acid, Pseudomonas sp. MA02, which assimilated S-(+)-mandelic acid as carbon and energy source, was isolated from soil. Using the fed-batch culture under optimal condition, R-(-)-mandelic acid was accumulated up to the maximum theoretical yield of 50% (30 g l-1) and entiomeric excess of 99.4%.

KW - Fed-batch fermentation

KW - Mandelic acid

KW - Optical resolution

KW - Pseudomonas sp

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JO - Biotechnology Letters

JF - Biotechnology Letters

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ER -

Optical resolution of RS-(±)-mandelic acid by pseudomonas sp

Abstract

Keywords

ASJC Scopus subject areas

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