Optical resolution of RS-(±)-mandelic acid by pseudomonas sp

Byung Yong Kim, Ki Chul Hwang, Hee Sang Song, Namhyun Chung, Won Gi Bang

    Research output: Contribution to journalArticlepeer-review

    15 Citations (Scopus)

    Abstract

    For the optical resolution of R-(-)-mandelic acid from (±)-mandelic acid, Pseudomonas sp. MA02, which assimilated S-(+)-mandelic acid as carbon and energy source, was isolated from soil. Using the fed-batch culture under optimal condition, R-(-)-mandelic acid was accumulated up to the maximum theoretical yield of 50% (30 g l-1) and entiomeric excess of 99.4%.

    Original languageEnglish
    Article number312873
    Pages (from-to)1871-1875
    Number of pages5
    JournalBiotechnology letters
    Volume22
    Issue number23
    DOIs
    Publication statusPublished - 2000

    Bibliographical note

    Funding Information:
    This work is partially supported by an intramural research fund of Korea University, Seoul, Korea.

    Keywords

    • Fed-batch fermentation
    • Mandelic acid
    • Optical resolution
    • Pseudomonas sp

    ASJC Scopus subject areas

    • Biotechnology
    • Bioengineering
    • Applied Microbiology and Biotechnology

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