Optimal level of continuous positive airway pressure: Auto-adjusting titration versus titration with a predictive equation

Seung Hoon Lee, Ji Ho Choi, Young Joon Jun, Jeong In Oh, Jong Yoon Jung, Gyu Ho Hwang, Soon Young Kwon, Heung Man Lee, Tae Hoon Kim, Sang Hag Lee

    Research output: Contribution to journalArticlepeer-review

    3 Citations (Scopus)

    Abstract

    Objectives: The aims of the present study were twofold. We sought to compare two methods of titrating the level of continuous positive airway pressure (CPAP)-auto-adjusting titration and titration using a predictive equation-with full-night manual titration used as the benchmark. We also investigated the reliability of the two methods in patients with obstructive sleep apnea syndrome (OSAS). Methods: Twenty consecutive adult patients with OSAS who had successful, full-night manual and auto-adjusting CPAP titration participated in this study. The titration pressure level was calculated with a previously developed predictive equation based on body mass index and apnea-hypopnea index. Results: The mean titration pressure levels obtained with the manual, auto-adjusting, and predictive equation methods were 9.0 ± 3.6, 9.4 ± 3.0, and 8.1 ± 1.6 cm H2O, respectively. There was a significant difference in the concordance within the range of ±2 cm H2O (p = 0.019) between both the auto-adjusting titration and the titration using the predictive equation compared to the full-night manual titration. However, there was no significant difference in the concordance within the range of ±1 cm H2O (p > 0.999). Conclusions: When compared to full-night manual titration as the standard method, auto-adjusting titration appears to be more reliable than using a predictive equation for determining the optimal CPAP level in patients with OSAS.

    Original languageEnglish
    Pages (from-to)339-343
    Number of pages5
    JournalAnnals of Otology, Rhinology and Laryngology
    Volume122
    Issue number5
    DOIs
    Publication statusPublished - 2013 May

    Bibliographical note

    Funding Information:
    From the Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Korea University, Seoul, Korea. This study was supported by a grant from the Korea Healthcare Technology R&D Project, Ministry for Health, Welfare and Family Affairs, Republic of Korea (A090084).

    Keywords

    • Adult
    • Body Mass Index
    • Continuous Positive Airway Pressure
    • Obstructive Sleep Apnea Syndrome
    • Polysomnography

    ASJC Scopus subject areas

    • Otorhinolaryngology

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