Optimal level of continuous positive airway pressure: Auto-adjusting titration versus titration with a predictive equation

Seung Hoon Lee; Ji Ho Choi; Young Joon Jun; Jeong In Oh; Jong Yoon Jung; Gyu Ho Hwang; Soon Young Kwon; Heung Man Lee; Tae Hoon Kim; Sang Hag Lee

doi:10.1177/000348941312200509

Optimal level of continuous positive airway pressure: Auto-adjusting titration versus titration with a predictive equation

Seung Hoon Lee, Ji Ho Choi, Young Joon Jun, Jeong In Oh, Jong Yoon Jung, Gyu Ho Hwang, Soon Young Kwon, Heung Man Lee, Tae Hoon Kim, Sang Hag Lee

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Objectives: The aims of the present study were twofold. We sought to compare two methods of titrating the level of continuous positive airway pressure (CPAP)-auto-adjusting titration and titration using a predictive equation-with full-night manual titration used as the benchmark. We also investigated the reliability of the two methods in patients with obstructive sleep apnea syndrome (OSAS). Methods: Twenty consecutive adult patients with OSAS who had successful, full-night manual and auto-adjusting CPAP titration participated in this study. The titration pressure level was calculated with a previously developed predictive equation based on body mass index and apnea-hypopnea index. Results: The mean titration pressure levels obtained with the manual, auto-adjusting, and predictive equation methods were 9.0 ± 3.6, 9.4 ± 3.0, and 8.1 ± 1.6 cm H2O, respectively. There was a significant difference in the concordance within the range of ±2 cm H2O (p = 0.019) between both the auto-adjusting titration and the titration using the predictive equation compared to the full-night manual titration. However, there was no significant difference in the concordance within the range of ±1 cm H2O (p > 0.999). Conclusions: When compared to full-night manual titration as the standard method, auto-adjusting titration appears to be more reliable than using a predictive equation for determining the optimal CPAP level in patients with OSAS.

Original language	English
Pages (from-to)	339-343
Number of pages	5
Journal	Annals of Otology, Rhinology and Laryngology
Volume	122
Issue number	5
DOIs	https://doi.org/10.1177/000348941312200509
Publication status	Published - 2013 May

Bibliographical note

Funding Information:
From the Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Korea University, Seoul, Korea. This study was supported by a grant from the Korea Healthcare Technology R&D Project, Ministry for Health, Welfare and Family Affairs, Republic of Korea (A090084).

Keywords

Adult
Body Mass Index
Continuous Positive Airway Pressure
Obstructive Sleep Apnea Syndrome
Polysomnography

ASJC Scopus subject areas

Otorhinolaryngology

Access to Document

10.1177/000348941312200509

Cite this

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title = "Optimal level of continuous positive airway pressure: Auto-adjusting titration versus titration with a predictive equation",

abstract = "Objectives: The aims of the present study were twofold. We sought to compare two methods of titrating the level of continuous positive airway pressure (CPAP)-auto-adjusting titration and titration using a predictive equation-with full-night manual titration used as the benchmark. We also investigated the reliability of the two methods in patients with obstructive sleep apnea syndrome (OSAS). Methods: Twenty consecutive adult patients with OSAS who had successful, full-night manual and auto-adjusting CPAP titration participated in this study. The titration pressure level was calculated with a previously developed predictive equation based on body mass index and apnea-hypopnea index. Results: The mean titration pressure levels obtained with the manual, auto-adjusting, and predictive equation methods were 9.0 ± 3.6, 9.4 ± 3.0, and 8.1 ± 1.6 cm H2O, respectively. There was a significant difference in the concordance within the range of ±2 cm H2O (p = 0.019) between both the auto-adjusting titration and the titration using the predictive equation compared to the full-night manual titration. However, there was no significant difference in the concordance within the range of ±1 cm H2O (p > 0.999). Conclusions: When compared to full-night manual titration as the standard method, auto-adjusting titration appears to be more reliable than using a predictive equation for determining the optimal CPAP level in patients with OSAS.",

keywords = "Adult, Body Mass Index, Continuous Positive Airway Pressure, Obstructive Sleep Apnea Syndrome, Polysomnography",

author = "Lee, {Seung Hoon} and Choi, {Ji Ho} and Jun, {Young Joon} and Oh, {Jeong In} and Jung, {Jong Yoon} and Hwang, {Gyu Ho} and Kwon, {Soon Young} and Lee, {Heung Man} and Kim, {Tae Hoon} and Lee, {Sang Hag}",

note = "Funding Information: From the Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Korea University, Seoul, Korea. This study was supported by a grant from the Korea Healthcare Technology R&D Project, Ministry for Health, Welfare and Family Affairs, Republic of Korea (A090084).",

year = "2013",

month = may,

doi = "10.1177/000348941312200509",

language = "English",

volume = "122",

pages = "339--343",

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T1 - Optimal level of continuous positive airway pressure

T2 - Auto-adjusting titration versus titration with a predictive equation

AU - Lee, Seung Hoon

AU - Choi, Ji Ho

AU - Jun, Young Joon

AU - Oh, Jeong In

AU - Jung, Jong Yoon

AU - Hwang, Gyu Ho

AU - Kwon, Soon Young

AU - Lee, Heung Man

AU - Kim, Tae Hoon

AU - Lee, Sang Hag

N1 - Funding Information: From the Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Korea University, Seoul, Korea. This study was supported by a grant from the Korea Healthcare Technology R&D Project, Ministry for Health, Welfare and Family Affairs, Republic of Korea (A090084).

PY - 2013/5

Y1 - 2013/5

N2 - Objectives: The aims of the present study were twofold. We sought to compare two methods of titrating the level of continuous positive airway pressure (CPAP)-auto-adjusting titration and titration using a predictive equation-with full-night manual titration used as the benchmark. We also investigated the reliability of the two methods in patients with obstructive sleep apnea syndrome (OSAS). Methods: Twenty consecutive adult patients with OSAS who had successful, full-night manual and auto-adjusting CPAP titration participated in this study. The titration pressure level was calculated with a previously developed predictive equation based on body mass index and apnea-hypopnea index. Results: The mean titration pressure levels obtained with the manual, auto-adjusting, and predictive equation methods were 9.0 ± 3.6, 9.4 ± 3.0, and 8.1 ± 1.6 cm H2O, respectively. There was a significant difference in the concordance within the range of ±2 cm H2O (p = 0.019) between both the auto-adjusting titration and the titration using the predictive equation compared to the full-night manual titration. However, there was no significant difference in the concordance within the range of ±1 cm H2O (p > 0.999). Conclusions: When compared to full-night manual titration as the standard method, auto-adjusting titration appears to be more reliable than using a predictive equation for determining the optimal CPAP level in patients with OSAS.

AB - Objectives: The aims of the present study were twofold. We sought to compare two methods of titrating the level of continuous positive airway pressure (CPAP)-auto-adjusting titration and titration using a predictive equation-with full-night manual titration used as the benchmark. We also investigated the reliability of the two methods in patients with obstructive sleep apnea syndrome (OSAS). Methods: Twenty consecutive adult patients with OSAS who had successful, full-night manual and auto-adjusting CPAP titration participated in this study. The titration pressure level was calculated with a previously developed predictive equation based on body mass index and apnea-hypopnea index. Results: The mean titration pressure levels obtained with the manual, auto-adjusting, and predictive equation methods were 9.0 ± 3.6, 9.4 ± 3.0, and 8.1 ± 1.6 cm H2O, respectively. There was a significant difference in the concordance within the range of ±2 cm H2O (p = 0.019) between both the auto-adjusting titration and the titration using the predictive equation compared to the full-night manual titration. However, there was no significant difference in the concordance within the range of ±1 cm H2O (p > 0.999). Conclusions: When compared to full-night manual titration as the standard method, auto-adjusting titration appears to be more reliable than using a predictive equation for determining the optimal CPAP level in patients with OSAS.

KW - Adult

KW - Body Mass Index

KW - Continuous Positive Airway Pressure

KW - Obstructive Sleep Apnea Syndrome

KW - Polysomnography

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SN - 0003-4894

VL - 122

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EP - 343

JO - Annals of Otology, Rhinology and Laryngology

JF - Annals of Otology, Rhinology and Laryngology

IS - 5

ER -

Optimal level of continuous positive airway pressure: Auto-adjusting titration versus titration with a predictive equation

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

Access to Document

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