TY - JOUR
T1 - Optimization of culture medium and conditions for Neo- fructooligosaccharides production by Penicillium citrinum
AU - Lim, Jung Soo
AU - Park, Man Chul
AU - Lee, Jong Ho
AU - Park, Seung Won
AU - Kim, Seung Wook
N1 - Funding Information:
Acknowledgements This study was supported by research grants from the Korea Science and Engineering Foundation (KOSEF) through the Applied Rheology Center (ARC), an official KOSEF-created engineering research center (ERC) at Korea University, Seoul, South Korea.
Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2005/10
Y1 - 2005/10
N2 - Culture medium and conditions were optimized to improve neo-fructooilgosaccharide (neo-FOS) production by Penicillium citrinum using Response Surface Methodology (RSM). The central composite designs using RSM were employed in this investigation. The quadratic models for neo-FOS production were obtained. Among culture media, optimal concentration of sucrose and yeast extract were found to be 12.65% and 2.90%, respectively, and predicted maximum value of neo-FOS production was 39.3 g/l. For culture conditions, optimal points of inoculum age (78.5 h), initial pH (7.34) and inoculum size (11.36% (v/v)) were determined and predicted maximum value of neo-FOS production was 40.6 g/l. By performing the culture under optimal culture media and conditions, actual neo-FOS production increased to 107%. It was also suggested that RSM can be used as a potential tool for optimization of factors in fermentation and food industry.
AB - Culture medium and conditions were optimized to improve neo-fructooilgosaccharide (neo-FOS) production by Penicillium citrinum using Response Surface Methodology (RSM). The central composite designs using RSM were employed in this investigation. The quadratic models for neo-FOS production were obtained. Among culture media, optimal concentration of sucrose and yeast extract were found to be 12.65% and 2.90%, respectively, and predicted maximum value of neo-FOS production was 39.3 g/l. For culture conditions, optimal points of inoculum age (78.5 h), initial pH (7.34) and inoculum size (11.36% (v/v)) were determined and predicted maximum value of neo-FOS production was 40.6 g/l. By performing the culture under optimal culture media and conditions, actual neo-FOS production increased to 107%. It was also suggested that RSM can be used as a potential tool for optimization of factors in fermentation and food industry.
KW - Neo-fructooligosaccharide
KW - Optimization
KW - Penicillium citrinum
KW - Response Surface Methodology
KW - Statistical analysis
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U2 - 10.1007/s00217-005-0070-6
DO - 10.1007/s00217-005-0070-6
M3 - Article
AN - SCOPUS:27844519774
SN - 1438-2377
VL - 221
SP - 639
EP - 644
JO - European Food Research and Technology
JF - European Food Research and Technology
IS - 5
ER -