Optimization of feed conditions in a 2.5-l fed-batch culture using rice oil to improve cephalosporin C production by Cephalosporium acremonium M25

Ri Kim Na; Soo Lim Jung; In Hong Suk; Wook Kim Seung

doi:10.1007/s11274-004-3852-2

Optimization of feed conditions in a 2.5-l fed-batch culture using rice oil to improve cephalosporin C production by Cephalosporium acremonium M25

Ri Kim Na
, Soo Lim Jung
, In Hong Suk
, Wook Kim Seung^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

Rice oil significantly affected cephalosporin C production in a 2.5-l bioreactor culture of Cephalosporium acremonium M25. To improve cephalosporin C production, the feed conditions of rice oil were optimized. Reducing the feed rate of rice oil improved cephalosporin C production to 1.01 g/l when the consumption rate of rice oil decreased. Overall, under optimal feed conditions in the 2.5-l fed-batch culture, cephalosporin C production increased about four times compared to before optimization.

Original language	English
Pages (from-to)	787-789
Number of pages	3
Journal	World Journal of Microbiology and Biotechnology
Volume	21
Issue number	5
DOIs	https://doi.org/10.1007/s11274-004-3852-2
Publication status	Published - 2005 Jul

Bibliographical note

Funding Information:
This study was supported by research grants from the Korea Science and Engineering Foundation (KOSEF) through the Applied Rheology Center (ARC), an official KOSEF-created engineering research center (ERC) at Korea University, Seoul, Korea.

Keywords

Cephalosporin C
Cephalosporium acremonium
Fed-batch
Feed conditions
Rice oil

ASJC Scopus subject areas

Biotechnology
Physiology
Applied Microbiology and Biotechnology

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10.1007/s11274-004-3852-2

Cite this

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title = "Optimization of feed conditions in a 2.5-l fed-batch culture using rice oil to improve cephalosporin C production by Cephalosporium acremonium M25",

abstract = "Rice oil significantly affected cephalosporin C production in a 2.5-l bioreactor culture of Cephalosporium acremonium M25. To improve cephalosporin C production, the feed conditions of rice oil were optimized. Reducing the feed rate of rice oil improved cephalosporin C production to 1.01 g/l when the consumption rate of rice oil decreased. Overall, under optimal feed conditions in the 2.5-l fed-batch culture, cephalosporin C production increased about four times compared to before optimization.",

keywords = "Cephalosporin C, Cephalosporium acremonium, Fed-batch, Feed conditions, Rice oil",

author = "Na, \{Ri Kim\} and Jung, \{Soo Lim\} and Suk, \{In Hong\} and Seung, \{Wook Kim\}",

note = "Funding Information: This study was supported by research grants from the Korea Science and Engineering Foundation (KOSEF) through the Applied Rheology Center (ARC), an official KOSEF-created engineering research center (ERC) at Korea University, Seoul, Korea.",

year = "2005",

month = jul,

doi = "10.1007/s11274-004-3852-2",

language = "English",

volume = "21",

pages = "787--789",

journal = "World Journal of Microbiology and Biotechnology",

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TY - JOUR

T1 - Optimization of feed conditions in a 2.5-l fed-batch culture using rice oil to improve cephalosporin C production by Cephalosporium acremonium M25

AU - Na, Ri Kim

AU - Jung, Soo Lim

AU - Suk, In Hong

AU - Seung, Wook Kim

N1 - Funding Information: This study was supported by research grants from the Korea Science and Engineering Foundation (KOSEF) through the Applied Rheology Center (ARC), an official KOSEF-created engineering research center (ERC) at Korea University, Seoul, Korea.

PY - 2005/7

Y1 - 2005/7

N2 - Rice oil significantly affected cephalosporin C production in a 2.5-l bioreactor culture of Cephalosporium acremonium M25. To improve cephalosporin C production, the feed conditions of rice oil were optimized. Reducing the feed rate of rice oil improved cephalosporin C production to 1.01 g/l when the consumption rate of rice oil decreased. Overall, under optimal feed conditions in the 2.5-l fed-batch culture, cephalosporin C production increased about four times compared to before optimization.

AB - Rice oil significantly affected cephalosporin C production in a 2.5-l bioreactor culture of Cephalosporium acremonium M25. To improve cephalosporin C production, the feed conditions of rice oil were optimized. Reducing the feed rate of rice oil improved cephalosporin C production to 1.01 g/l when the consumption rate of rice oil decreased. Overall, under optimal feed conditions in the 2.5-l fed-batch culture, cephalosporin C production increased about four times compared to before optimization.

KW - Cephalosporin C

KW - Cephalosporium acremonium

KW - Fed-batch

KW - Feed conditions

KW - Rice oil

UR - https://www.scopus.com/pages/publications/23044517043

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DO - 10.1007/s11274-004-3852-2

M3 - Article

AN - SCOPUS:23044517043

SN - 0959-3993

VL - 21

SP - 787

EP - 789

JO - World Journal of Microbiology and Biotechnology

JF - World Journal of Microbiology and Biotechnology

IS - 5

ER -

Optimization of feed conditions in a 2.5-l fed-batch culture using rice oil to improve cephalosporin C production by Cephalosporium acremonium M25

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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