Optimization of pressurized liquid extraction for spicatoside A in Liriope platyphylla

Seung Hyun Kim; Ho Kyung Kim; Eun Sun Yang; Ki Yong Lee; Sang Du Kim; Young Choong Kim; Sang Hyun Sung

doi:10.1016/j.seppur.2009.11.016

Optimization of pressurized liquid extraction for spicatoside A in Liriope platyphylla

Seung Hyun Kim
, Ho Kyung Kim
, Eun Sun Yang
, Ki Yong Lee
, Sang Du Kim
, Young Choong Kim
, Sang Hyun Sung^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

26 Citations (Scopus)

Abstract

Method development based on pressurized liquid extraction technique was investigated for the extraction of spicatoside A from Liriope platyphylla. Determination of spicatoside A was carried out by high performance liquid chromatography coupled with charged aerosol detector. Central composite design consisting of 15 experimental points in triplicate was applied to evaluated the effects of three independent variables, namely extraction time (min), extraction temperature (°C) and ethanol concentration (%) on the acquired content of spicatoside A. Response surface analysis indicated that the highest predicted content of spicatoside A might be 0.0161% of the optimized extract at extraction time 20 min, extraction temperature 130 °C and ethanol concentration 86%. Under this optimal condition, the experimental value was 0.0157%, which agrees with the predicted one by analysis of variance.

Original language	English
Pages (from-to)	168-172
Number of pages	5
Journal	Separation and Purification Technology
Volume	71
Issue number	2
DOIs	https://doi.org/10.1016/j.seppur.2009.11.016
Publication status	Published - 2010 Feb 18
Externally published	Yes

Keywords

Charged aerosol detector
Liriope platyphylla
Pressurized liquid extraction
Spicatoside A

ASJC Scopus subject areas

Analytical Chemistry
Filtration and Separation

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10.1016/j.seppur.2009.11.016

Cite this

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title = "Optimization of pressurized liquid extraction for spicatoside A in Liriope platyphylla",

abstract = "Method development based on pressurized liquid extraction technique was investigated for the extraction of spicatoside A from Liriope platyphylla. Determination of spicatoside A was carried out by high performance liquid chromatography coupled with charged aerosol detector. Central composite design consisting of 15 experimental points in triplicate was applied to evaluated the effects of three independent variables, namely extraction time (min), extraction temperature (°C) and ethanol concentration (\%) on the acquired content of spicatoside A. Response surface analysis indicated that the highest predicted content of spicatoside A might be 0.0161\% of the optimized extract at extraction time 20 min, extraction temperature 130 °C and ethanol concentration 86\%. Under this optimal condition, the experimental value was 0.0157\%, which agrees with the predicted one by analysis of variance.",

keywords = "Charged aerosol detector, Liriope platyphylla, Pressurized liquid extraction, Spicatoside A",

author = "Kim, \{Seung Hyun\} and Kim, \{Ho Kyung\} and Yang, \{Eun Sun\} and Lee, \{Ki Yong\} and Kim, \{Sang Du\} and Kim, \{Young Choong\} and Sung, \{Sang Hyun\}",

year = "2010",

month = feb,

day = "18",

doi = "10.1016/j.seppur.2009.11.016",

language = "English",

volume = "71",

pages = "168--172",

journal = "Separation and Purification Technology",

issn = "1383-5866",

publisher = "Elsevier B.V.",

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}

TY - JOUR

T1 - Optimization of pressurized liquid extraction for spicatoside A in Liriope platyphylla

AU - Kim, Seung Hyun

AU - Kim, Ho Kyung

AU - Yang, Eun Sun

AU - Lee, Ki Yong

AU - Kim, Sang Du

AU - Kim, Young Choong

AU - Sung, Sang Hyun

PY - 2010/2/18

Y1 - 2010/2/18

N2 - Method development based on pressurized liquid extraction technique was investigated for the extraction of spicatoside A from Liriope platyphylla. Determination of spicatoside A was carried out by high performance liquid chromatography coupled with charged aerosol detector. Central composite design consisting of 15 experimental points in triplicate was applied to evaluated the effects of three independent variables, namely extraction time (min), extraction temperature (°C) and ethanol concentration (%) on the acquired content of spicatoside A. Response surface analysis indicated that the highest predicted content of spicatoside A might be 0.0161% of the optimized extract at extraction time 20 min, extraction temperature 130 °C and ethanol concentration 86%. Under this optimal condition, the experimental value was 0.0157%, which agrees with the predicted one by analysis of variance.

AB - Method development based on pressurized liquid extraction technique was investigated for the extraction of spicatoside A from Liriope platyphylla. Determination of spicatoside A was carried out by high performance liquid chromatography coupled with charged aerosol detector. Central composite design consisting of 15 experimental points in triplicate was applied to evaluated the effects of three independent variables, namely extraction time (min), extraction temperature (°C) and ethanol concentration (%) on the acquired content of spicatoside A. Response surface analysis indicated that the highest predicted content of spicatoside A might be 0.0161% of the optimized extract at extraction time 20 min, extraction temperature 130 °C and ethanol concentration 86%. Under this optimal condition, the experimental value was 0.0157%, which agrees with the predicted one by analysis of variance.

KW - Charged aerosol detector

KW - Liriope platyphylla

KW - Pressurized liquid extraction

KW - Spicatoside A

UR - https://www.scopus.com/pages/publications/74849093090

U2 - 10.1016/j.seppur.2009.11.016

DO - 10.1016/j.seppur.2009.11.016

M3 - Article

AN - SCOPUS:74849093090

SN - 1383-5866

VL - 71

SP - 168

EP - 172

JO - Separation and Purification Technology

JF - Separation and Purification Technology

IS - 2

ER -

Optimization of pressurized liquid extraction for spicatoside A in Liriope platyphylla

Abstract

Keywords

ASJC Scopus subject areas

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