Abstract
In terms of quantifying screening results, conventional 96-well cell culture plates have limitations, such as the inability to tackle the placement problem of organoids in each well or each ECM hydrogel. To overcome this issue by uniformly positioning organoids in the plate, we drilled a hole in the middle of each well and injected the same number of cells and volume of ECM in each well. Organoids derived from epithelial ovarian cancer (EOC) were used as a source for drug screening, and we were able to acquire quite uniform results at each drug concentration.
| Original language | English |
|---|---|
| Title of host publication | MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 1199-1200 |
| Number of pages | 2 |
| ISBN (Electronic) | 9781733419048 |
| Publication status | Published - 2022 |
| Event | 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2022 - Hybrid, Hangzhou, China Duration: 2022 Oct 23 → 2022 Oct 27 |
Publication series
| Name | MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
|---|
Conference
| Conference | 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2022 |
|---|---|
| Country/Territory | China |
| City | Hybrid, Hangzhou |
| Period | 22/10/23 → 22/10/27 |
Bibliographical note
Publisher Copyright:© 2022 MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences. All rights reserved.
Keywords
- Drug Screening
- Patient-derived Organoid
- Personalized Medicine
- Uniform Assess
ASJC Scopus subject areas
- Chemical Engineering (miscellaneous)
- Bioengineering
- General Chemistry
- Control and Systems Engineering
