Oxidation of pyrene using a hemoglobin-catalyzed biocatalytic reaction

Haein Keum, Guyoung Kang, Namhyun Chung

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)


The efficiency to remove polycyclic aromatic hydrocarbons (PAHs) was determined using a hemoglobin-catalyzed biocatalytic reaction. The present study employed pyrene as a model of PAHs to study its oxidative removal in the presence of H2O2 and hemoglobin in mass ratio of 3:1. The extent of pyrene removal reached up to 91.1% in the presence of H2O2 and hemoglobin. However, the extent of pyrene removal was 21.3% in the presence of H2O2 only. The results indicate that pyrene removal might be due to pyrene oxidation by the biocatalytic reaction. Overall, this study demonstrated that hemoglobin-catalyzed biocatalytic reactions could remediate pyrene effectively.

Original languageEnglish
Pages (from-to)505-508
Number of pages4
JournalApplied Biological Chemistry
Issue number5
Publication statusPublished - 2017 Oct 1

Bibliographical note

Funding Information:
Acknowledgment This study was supported by the Korea Basic Science Institute (KBSI) and was partially supported by a grant from Hankuk University of Foreign Studies.

Publisher Copyright:
© 2017, The Korean Society for Applied Biological Chemistry.


  • Biocatalytic reaction
  • Hemoglobin
  • Hydrogen peroxide
  • Oxidation
  • Pyrene

ASJC Scopus subject areas

  • General Biochemistry,Genetics and Molecular Biology
  • Organic Chemistry


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