Palladium-catalyzed tandem Heck and aldol reactions between 2-bromobenzaldehydes and functionalized alkenes leading to naphthalenes

Chan Sik Cho; Dong Kwon Lim; Jiao Qiang Zhang; Tae Jeong Kim; Sang Chul Shim

doi:10.1016/j.tetlet.2004.05.112

Palladium-catalyzed tandem Heck and aldol reactions between 2-bromobenzaldehydes and functionalized alkenes leading to naphthalenes

Chan Sik Cho, Dong Kwon Lim, Jiao Qiang Zhang, Tae Jeong Kim, Sang Chul Shim

Research output: Contribution to journal › Article › peer-review

31 Citations (Scopus)

Abstract

2-Bromobenzaldehydes react with an array of suitably functionalized alkenes in the presence of a catalytic amount of a palladium catalyst together with a base to afford the corresponding naphthalenes in moderate to good yields.

Original language	English
Pages (from-to)	5653-5656
Number of pages	4
Journal	Tetrahedron Letters
Volume	45
Issue number	29
DOIs	https://doi.org/10.1016/j.tetlet.2004.05.112
Publication status	Published - 2004 Jul 12
Externally published	Yes

Keywords

2-Bromobenzaldehydes
Functionalized alkenes
Heck-aldol reaction
Naphthalenes
Palladium catalyst

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tetlet.2004.05.112

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title = "Palladium-catalyzed tandem Heck and aldol reactions between 2-bromobenzaldehydes and functionalized alkenes leading to naphthalenes",

abstract = "2-Bromobenzaldehydes react with an array of suitably functionalized alkenes in the presence of a catalytic amount of a palladium catalyst together with a base to afford the corresponding naphthalenes in moderate to good yields.",

keywords = "2-Bromobenzaldehydes, Functionalized alkenes, Heck-aldol reaction, Naphthalenes, Palladium catalyst",

author = "Cho, {Chan Sik} and Lim, {Dong Kwon} and Zhang, {Jiao Qiang} and Kim, {Tae Jeong} and Shim, {Sang Chul}",

note = "Funding Information: This work was supported by the Brain Korea 21 Project in 2003 and a Korea Research Foundation Grant (KRF-2002-070-C00055). C.S.C. gratefully acknowledges a MOE-KRF Research Professor Program (KRF-2001-050-D00015). ",

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doi = "10.1016/j.tetlet.2004.05.112",

language = "English",

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journal = "Tetrahedron Letters",

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T1 - Palladium-catalyzed tandem Heck and aldol reactions between 2-bromobenzaldehydes and functionalized alkenes leading to naphthalenes

AU - Cho, Chan Sik

AU - Lim, Dong Kwon

AU - Zhang, Jiao Qiang

AU - Kim, Tae Jeong

AU - Shim, Sang Chul

N1 - Funding Information: This work was supported by the Brain Korea 21 Project in 2003 and a Korea Research Foundation Grant (KRF-2002-070-C00055). C.S.C. gratefully acknowledges a MOE-KRF Research Professor Program (KRF-2001-050-D00015).

PY - 2004/7/12

Y1 - 2004/7/12

N2 - 2-Bromobenzaldehydes react with an array of suitably functionalized alkenes in the presence of a catalytic amount of a palladium catalyst together with a base to afford the corresponding naphthalenes in moderate to good yields.

AB - 2-Bromobenzaldehydes react with an array of suitably functionalized alkenes in the presence of a catalytic amount of a palladium catalyst together with a base to afford the corresponding naphthalenes in moderate to good yields.

KW - 2-Bromobenzaldehydes

KW - Functionalized alkenes

KW - Heck-aldol reaction

KW - Naphthalenes

KW - Palladium catalyst

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U2 - 10.1016/j.tetlet.2004.05.112

DO - 10.1016/j.tetlet.2004.05.112

M3 - Article

AN - SCOPUS:3042677509

SN - 0040-4039

VL - 45

SP - 5653

EP - 5656

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 29

ER -

Palladium-catalyzed tandem Heck and aldol reactions between 2-bromobenzaldehydes and functionalized alkenes leading to naphthalenes

Abstract

Keywords

ASJC Scopus subject areas

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